乳房重建术后慢性术后疼痛:评论与批评。

Chronic postsurgical pain following breast reconstruction: a commentary and critique.

机构信息

Department of Physical Medicine & Rehabilitation, University of Michigan Health Systems, 325 E. Eisenhower Pkwy., Ann Arbor, MI, 48108, USA.

出版信息

Breast Cancer Res Treat. 2018 Jun;169(2):209-216. doi: 10.1007/s10549-018-4687-0. Epub 2018 Jan 30.

Abstract

In line with other major surgeries including breast cancer surgery (BCS), recent studies suggest a striking rate of chronic postsurgical pain (CPSP) following breast reconstruction. This commentary will critically examine evidence for the degree to which the prevalence of CPSP following breast reconstruction is directly attributable to reconstructive surgery. The discussion will trace similarities and distinctions between breast reconstruction and BCS in considering the risk for CPSP, and describe recent advances in the definition of CPSP, highlighting methodological limitations in the general investigation of CPSP, which also characterize the study of CPSP more specifically for breast reconstruction outcome. A convenience sample of relevant studies examining CPSP following breast reconstruction reveals inadequate evidence to support a serious concern for reconstruction-induced CPSP and further that these studies fail to adhere to recommended methodological standards to effectively isolate surgery as the etiology of persistent pain reported by women following reconstructive surgery. Suggestions for future exploration of problematic chronic pain after breast reconstruction are considered.

摘要

与乳腺癌手术 (BCS) 等其他重大手术一样,最近的研究表明,乳房重建后慢性术后疼痛 (CPSP) 的发生率很高。本评论将批判性地审视以下证据:在多大程度上,乳房重建后 CPSP 的患病率直接归因于重建手术。在考虑 CPSP 的风险时,该讨论将追踪乳房重建和 BCS 之间的相似点和区别,并描述 CPSP 定义的最新进展,突出 CPSP 一般研究中的方法学限制,这些限制也更具体地描述了 CPSP 研究,特别是针对乳房重建结果。对乳房重建后 CPSP 进行检查的相关研究便利样本显示,没有足够的证据支持对重建引起的 CPSP 的严重担忧,而且这些研究未能遵守建议的方法学标准,无法有效地将手术作为女性在重建手术后报告的持续性疼痛的病因进行隔离。还考虑了对乳房重建后出现的问题性慢性疼痛进行未来探索的建议。

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