Patten R M, Van Allen M, Mack L A, Wilson D, Nyberg D, Hirsch J, Viamont T
AJR Am J Roentgenol. 1986 May;146(5):1019-24. doi: 10.2214/ajr.146.5.1019.
Limb-Body Wall Complex is a complicated fetal malformation with the essential features of neural-tube defects, body-wall disruption, and limb abnormalities. This complex should be distinguished from other body-wall defects including omphalocele and gastroschisis since the prognosis for limb-body wall complex is uniformly poor. For 13 cases of this unusual fetal anomaly, sonographic, radiologic, and pathologic findings were correlated. Thoracic or abdominal body-wall defects, neural-tube abnormalities, severe scoliosis, positional deformities, and abnormalities of fetal membranes were consistently demonstrated on in utero sonograms. Results show that the diagnosis of limb-body wall complex can be made by prenatal sonography.
肢体-体壁复合体是一种复杂的胎儿畸形，其基本特征包括神经管缺陷、体壁中断和肢体异常。由于肢体-体壁复合体的预后普遍较差，因此应将其与其他体壁缺陷（包括脐膨出和腹裂）区分开来。对于13例这种罕见的胎儿异常病例，对超声、放射学和病理学检查结果进行了对比。产前超声检查始终显示出胸壁或腹壁缺陷、神经管异常、严重脊柱侧弯、体位畸形以及胎膜异常。结果表明，产前超声检查可对肢体-体壁复合体作出诊断。
