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一例累及脚趾的罕见大型皮肤软骨样汗腺腺瘤:病例报告

A rare large cutaneous chondroid syringoma involving a toe: A case report.

作者信息

Lu Hui, Chen Li-Feng, Chen Qiang, Shen Hui, Liu Zhenfeng

机构信息

Department of Hand Surgery Department of Medical Engineering PET Center, The First Affiliated Hospital, College of Medicine, Zhejiang University Department of Hand Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang Province, People's Republic of China.

出版信息

Medicine (Baltimore). 2018 Feb;97(5):e9825. doi: 10.1097/MD.0000000000009825.

DOI:10.1097/MD.0000000000009825
PMID:29384887
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5805459/
Abstract

RATIONALE

Chondroid syringoma (CS) occurs mostly on the face and neck, and rarely occurs in the toe. Malignant CS is invasive, grows quickly, and has a high recurrence rate. The presence of a bilobed CS in 1 toe has never been reported in the literature.

PATIENT CONCERNS

A 72-year-old male patient presented with a mass in a third toe of his right foot. The mass had slowly grown in 2 years. He felt mild pain and the mass occupied most of the tip of the toe.

DIAGNOSES

Radiographs showed a large soft-tissue mass in the third toe of his right foot without any bone destruction. Ultrasonogram showed 2 partly fused hypoechoic masses within the lesion. The mass was therefore diagnosed as a benign CS.

INTERVENTIONS

We amputated the toe with the mass under local anesthesia. The postoperative pathohistological examinations confirmed that the lesion was a bipartite CS exhibiting active cellular proliferation.

OUTCOMES

Two years after surgery, there was no tumor recurrence.

LESSONS

CS can also present as multiple adjacent masses. Complete surgical resection and long-term follow-up are essential.

摘要

原理

软骨样汗腺腺瘤(CS)多发生于面部和颈部,极少发生于脚趾。恶性CS具有侵袭性,生长迅速,复发率高。文献中从未报道过1个脚趾出现双叶状CS的情况。

患者情况

一名72岁男性患者,右足第三趾出现肿物。该肿物在2年内缓慢生长。他感到轻度疼痛,肿物占据了大部分趾尖。

诊断

X线片显示右足第三趾有一个大的软组织肿物,无任何骨质破坏。超声检查显示病变内有2个部分融合的低回声肿物。因此,该肿物被诊断为良性CS。

干预措施

我们在局部麻醉下切除了有肿物的脚趾。术后病理组织学检查证实病变为二分叶状CS,表现为活跃的细胞增殖。

结果

术后2年,无肿瘤复发。

经验教训

CS也可表现为多个相邻肿物。完整的手术切除和长期随访至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/0aa503b116c8/medi-97-e9825-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/f26ce39cd0ca/medi-97-e9825-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/71f7da28aa73/medi-97-e9825-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/57395d65e571/medi-97-e9825-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/83642c2cf2e0/medi-97-e9825-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/718e6edf3fd3/medi-97-e9825-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/0aa503b116c8/medi-97-e9825-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/f26ce39cd0ca/medi-97-e9825-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/71f7da28aa73/medi-97-e9825-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/57395d65e571/medi-97-e9825-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/83642c2cf2e0/medi-97-e9825-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/718e6edf3fd3/medi-97-e9825-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/5805459/0aa503b116c8/medi-97-e9825-g006.jpg

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Malignant chondroid syringoma of the pinna.耳廓恶性软骨样汗腺螺旋腺瘤
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A rare case of malignant chondroid syringoma of scalp.一例罕见的头皮恶性软骨样汗腺螺旋瘤。
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Myoepithelial carcinoma of pharynx expressing KIT and PDGFRA.表达KIT和PDGFRA的咽肌上皮癌
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Malignant chondroid syringoma of the face with bone invasion.
Am J Dermatopathol. 2013 May;35(3):395-8. doi: 10.1097/DAD.0b013e318274393d.
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Myoepithelioma of the skull: a case report.颅骨肌上皮瘤:一例报告。
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t(19;22)(q13;q12) Translocation leading to the novel fusion gene EWSR1-ZNF444 in soft tissue myoepithelial carcinoma.t(19;22)(q13;q12)易位导致软组织肌上皮癌中出现新的融合基因EWSR1-ZNF444 。
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