Departments of Neurological Surgery (Drs Mac Donald, Coppel, and Temkin, Messrs Barber, Panks, and Zalewski, and Ms Sun) and Biostatistics (Dr Temkin), University of Washington, Seattle; Departments of Radiology (Dr Wright) and Psychiatry and Behavioral Health (Dr De Lacy), Seattle Children's Hospital, Seattle, Washington; and Seattle Children's Research Institute, Seattle, Washington (Mr Ottinger and Ms Peck).
J Head Trauma Rehabil. 2018 Nov/Dec;33(6):E1-E10. doi: 10.1097/HTR.0000000000000381.
Prior work suggests that younger athletes may be more vulnerable to postconcussive syndrome. We investigated measures of clinical outcome and quantitative volumetric imaging in 10- to 14-year-old adolescent athletes to better understand the impact of concussion on this younger population.
Outpatient clinics.
Ten- to 14-year-old symptomatic pediatric sports concussion patients and typically developing active controls.
Prospective, observational multiclinic study.
Demographics, magnetic resonance imaging, clinical assessments (neurocognitive function, postconcussive symptoms, mental health symptoms, quality of life).
Neuropsychological performance was comparable between groups while symptoms of mental health were discriminating and comprised the top regression model describing factors related to overall health behavior impairment. Concussion patients had smaller total brain volume as well as total intracranial volume in comparison with controls even though there was no difference on measures of natural development (age, height, weight, education, gender, and handedness).
Findings indicate that 10- to 14-year-old concussion patients symptomatic at 1 month more likely exhibit mental health symptoms impairing health behavior than cognitive dysfunction. There may be a vulnerability for those with smaller brain volumes at the time of the exposure. The study provides new data to support further investigation into risk factors for prolonged symptoms in this younger athlete population.
先前的研究表明，年轻运动员可能更容易受到脑震荡后综合征的影响。我们研究了 10 至 14 岁青少年运动员的临床结果和定量容积成像测量指标，以更好地了解脑震荡对这一年轻人群的影响。
门诊诊所。
10 至 14 岁有症状的儿科运动性脑震荡患者和正常发育的活跃对照组。
前瞻性、观察性多诊所研究。
人口统计学资料、磁共振成像、临床评估（神经认知功能、脑震荡后症状、心理健康症状、生活质量）。
与对照组相比，神经心理学表现无差异，而心理健康症状具有鉴别力，是描述与整体健康行为障碍相关因素的最佳回归模型。与对照组相比，脑震荡患者的总脑容量和总颅内容量更小，尽管在自然发育方面（年龄、身高、体重、教育、性别和惯用手）没有差异。
研究结果表明，1 个月时有症状的 10 至 14 岁脑震荡患者更有可能出现心理健康症状，影响健康行为，而不是认知功能障碍。那些在暴露时大脑体积较小的人可能更容易受到影响。该研究提供了新的数据，支持进一步研究这个年轻运动员群体中症状持续时间的危险因素。
