Verma Ajay Kumar, Purbey Om Prakash, Kureel Shiv Narain, Gupta Archika, Pandey Anand, Sunil Kanoujia, Chaubey Digamber
Department of Pediatric Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
J Indian Assoc Pediatr Surg. 2018 Jan-Mar;23(1):32-35. doi: 10.4103/jiaps.JIAPS_75_17.
Roux-en-Y hepaticojejunostomy has been a gold standard to establish biliary-enteric anastomosis for various surgical indications, but associated with variable incidences of cholangitis. This experimental study was conducted to report a modification in Roux-en-Y anastomosis for possible better alternative to provide antireflux procedure after Roux-en-Y biliary-enteric anastomosis with the aim to minimize the possibility of reflux and its consequences.
For experimental study, the required fresh segment of Lamb's small intestine was procured. Three sets of Roux-en-Y anastomosis were created for each experiment. In set 1, there was simple Roux-en-Y anastomosis. In set 2, Roux-en-Y anastomosis along with 4-5 cm long spur between the hepatic and duodenal limbs was created. In set 3, in addition to Roux-en-Y with creation of spur, additional antireflux mechanism was created at the junction of upper two-third and lower one-third of the hepatic limb. Saline mixed contrast was infused by infusion pump to raise the intraluminal pressure to more than 10 cm of HO. X-ray was taken at that time.
In set 1, all preparations demonstrated reflux of contrast in the hepatic limb. The set 2 also demonstrated the same findings of 100% reflux in the hepatic limb. In set 3, No reflux was observed in 8 (80%) preparations while remaining 2 (20%) preparations reveal partial reflux.
This experimental study suggests that the provision of spur and additional valve may be able to decrease the possibility of reflux in Roux-en-Y biliary-enteric anastomosis.
对于各种手术适应症,Roux-en-Y肝空肠吻合术一直是建立胆肠吻合的金标准,但胆管炎的发生率各不相同。本实验研究旨在报告一种Roux-en-Y吻合术的改良方法,作为一种可能更好的替代方案,在Roux-en-Y胆肠吻合术后提供抗反流程序,以尽量减少反流及其后果的可能性。
为进行实验研究,获取所需的新鲜羊小肠段。每次实验创建三组Roux-en-Y吻合术。在第1组中,进行简单的Roux-en-Y吻合术。在第2组中,创建Roux-en-Y吻合术,并在肝管和十二指肠支之间设置4-5厘米长的分支。在第3组中,除了创建带有分支的Roux-en-Y吻合术外,在肝管上三分之二和下三分之一交界处还创建了额外的抗反流机制。通过输液泵注入盐水混合造影剂,将腔内压力提高到超过10厘米水柱。此时进行X光检查。
在第1组中,所有制剂均显示造影剂反流至肝管。第2组也显示肝管反流率为100%。在第3组中,8例(80%)制剂未观察到反流,其余2例(20%)制剂显示部分反流。
本实验研究表明,设置分支和额外的瓣膜可能能够降低Roux-en-Y胆肠吻合术中反流的可能性。