Hogan D J, Epstein J D, Lane P R
CMAJ. 1986 May 1;134(9):1025-8.
To document the persistence of perioral dermatitis at dermatology clinics at University Hospital, Saskatoon, we reviewed the charts of all patients with the condition seen between January 1983 and March 1985. Patients with rosacea referred to the clinics during the same period were used as a comparison group. A total of 80 patients with perioral dermatitis and 117 patients with rosacea were seen during the study period; most were female. Those with perioral dermatitis were significantly younger and had a significantly shorter mean duration of the eruption before presentation than those with rosacea (p less than 0.001). The distribution of the lesions was different in the two groups. Sixty-eight (85%) of the patients with perioral dermatitis and 45 (38%) of those with rosacea had used topical corticosteroids, a postulated risk factor for perioral dermatitis; the use of potent topical corticosteroids was frequent in both groups. Despite continuing medical education on the dangers of chronic use of these agents for eruptions on the face, physicians continue to prescribe them.
为记录萨斯卡通市大学医院皮肤科门诊口周皮炎的持续情况，我们查阅了1983年1月至1985年3月期间所有患有该疾病患者的病历。将同期转诊至该门诊的酒渣鼻患者作为对照组。在研究期间，共诊治了80例口周皮炎患者和117例酒渣鼻患者；大多数为女性。口周皮炎患者比酒渣鼻患者明显年轻，且就诊前皮疹的平均持续时间明显更短（p<0.001）。两组的皮损分布不同。68例（85%）口周皮炎患者和45例（38%）酒渣鼻患者曾使用外用糖皮质激素，这是口周皮炎的一个假定危险因素；两组中强效外用糖皮质激素的使用都很常见。尽管一直在进行关于长期使用这些药物治疗面部皮疹危险性的医学继续教育，但医生仍继续开具此类药物。
