Arutjunow V
Hautarzt. 1978 Feb;29(2):89-91.
Perioral dermatitis was diagnosed in 329 patients. Sparing a thin white strip round the red border of the lips erythemas with papules and pseudopustules are arising around the mouth, on nose, eyes, chin, forehead, cheeks and the lateral parts of the neck. The duration of the infection ranged from two weeks up to three years. In many patients the following allergens were detected by patch testing: cosmetics, dental pastes, washing powders, chloric water, mohair, synthetics, and flowers. In 80 patients demodex was discovered. Its role in the pathogenesis of perioral dermatitis is doubtful. Biopsis were taken from 10 patients. Treatment with liquid nitrogen gives good results while antibiotics and corticosteroids are of little effect.
329例患者被诊断为口周皮炎。在口周、鼻、眼、下巴、额头、脸颊及颈部外侧出现红斑，伴有丘疹和假脓疱，围绕嘴唇红色边缘保留一条窄的白色条纹。感染持续时间从两周到三年不等。通过斑贴试验在许多患者中检测到以下过敏原：化妆品、牙膏、洗衣粉、氯水、马海毛、合成纤维和花卉。在80例患者中发现了蠕形螨。其在口周皮炎发病机制中的作用尚不确定。对10例患者进行了活检。液氮治疗效果良好，而抗生素和皮质类固醇效果不佳。
