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铜合金对感染和医院环境中分离的 种的抗菌作用。

Antimicrobial effect of copper alloys on species isolated from infections and hospital environment.

机构信息

1Chair of Microbiology, Faculty of Medicine, Jagiellonian University Medical College, ul. Czysta 18, 31-121 Kraków, Poland.

2Chair of Immunology, Faculty of Medicine, Jagiellonian University Medical College, ul. Czysta 18, 31-121 Kraków, Poland.

出版信息

Antimicrob Resist Infect Control. 2018 Jan 22;7:10. doi: 10.1186/s13756-018-0300-x. eCollection 2018.

Abstract

BACKGROUND

An increased proportion of Gram-negative bacteria have recently been reported among etiologic agents of infection. In Poland, is a big problem for hospitals, especially intensive care units. Touch surfaces made from materials with antimicrobial properties, especially copper alloys, are recommended as a supplementary method of increasing biological safety in the hospital environment.

AIM OF THE STUDY

The objective of this study is to determine the susceptibility to selected copper alloys of three clinical strains, one and an strain isolated from the hospital environment.

MATERIAL AND METHOD

The modification of the Japanese Standard, which the ISO 22196:2011 norm was used for testing antimicrobial properties of CuZn37, CuSn6 and CuNi18Zn20 and Cu-ETP and stainless steel as positive and negative control, respectively.

RESULTS

The highest cidal efficiency, expressed as both time and the degree of reduction of the initial suspension density, against all of the tested strains was found for ETP copper. But, the results of our study also confirmed effective activity (bacteriocidal or bacteriostatic) of copper alloys selected for the study, contrary to the stainless steel. The reduction in bacterial suspension density is significantly different depending on the strain and copper alloy composition.

CONSLUSIONS

The results of our study confirmed the effective antibacterial activity of copper and its selected alloys against clinical and strains, and strain isolated from the hospital environment.

摘要

背景

最近有报道称,感染病原体中革兰氏阴性菌的比例有所增加。在波兰,这对医院,尤其是重症监护病房来说是一个大问题。具有抗菌性能的触摸表面材料,尤其是铜合金,被推荐作为增加医院环境生物安全性的补充方法。

研究目的

本研究的目的是确定三种临床分离株、一种医院环境分离株和一种临床分离株对三种铜合金的敏感性。

材料和方法

采用日本标准的改良方法,使用 ISO 22196:2011 标准测试 CuZn37、CuSn6 和 CuNi18Zn20 以及 Cu-ETP 和不锈钢的抗菌性能,分别作为阳性和阴性对照。

结果

所有测试的菌株中,铜合金 ETP 的杀菌效率最高,表现为时间和初始悬浮密度降低的程度。但是,我们的研究结果也证实了所选铜合金具有有效的抗菌活性(杀菌或抑菌),而不锈钢则没有。细菌悬浮液密度的降低取决于菌株和铜合金的成分,存在显著差异。

结论

我们的研究结果证实了铜及其选定合金对临床分离株、医院环境分离株和分离株的有效抗菌活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853a/5778618/755726bfafb8/13756_2018_300_Fig1_HTML.jpg

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