Roghani Farshad, Tajik Mohammad Nasim, Khosravi Alireza
Department of Interventional Cardiology, Isfahan University of Medical Sciences, Isfahan, Iran.
Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2017 Dec 26;6:159. doi: 10.4103/abr.abr_164_16. eCollection 2017.
Coronary artery disease (CAD) is multifactorial disease, in which thrombotic occlusion and calcification occur usually. New strategies have been made for diagnosis and treatment of CAD, such as transradial catheterization. Hemostasis could be done in two approaches: traditional and patent. Our aim is to find the best approach with lowest complication.
In a comparative study, 120 patients were recruited and divided randomly into two subgroups, including traditional group (60 patients; 24 females, 36 males; mean age: 64.35 ± 10.56 years) and patent group (60 patients; 28 females, 32 males; mean age: 60.15 ± 8.92 years). All demographic data including age, gender, body mass index, and CAD-related risk factors (smoking, diabetes, hypertension) and technical data including the number of catheters, procedure duration, and hemostatic compression time and clinical outcomes (radial artery occlusion [RAO], hematoma, bleeding) were collected. Data were analyzed by SPSS version 16.
Our findings revealed that the incidence of RAO was significantly lower in patent groups compared with traditional group ( = 0.041). Furthermore, the difference incidence of RAO was higher in early occlusion compare with late one ( = 0.041). Moreover, there were significant relationship between some factors in patients of traditional group with occlusion (gender [ = 0.038], age [ = 0.031], diabetes mellitus [ = 0.043], hemostatic compression time [ = 0.036]) as well as in patent group (age [ = 0.009], hypertension [ = 0.035]).
Our findings showed that RAO, especially type early is significantly lower in patent method compared classic method; and patent hemostasis is the safest method and good alternative for classical method.
冠状动脉疾病（CAD）是一种多因素疾病，通常会发生血栓闭塞和钙化。已经制定了CAD诊断和治疗的新策略，如经桡动脉导管插入术。止血可通过两种方法进行：传统方法和专利方法。我们的目标是找到并发症最少的最佳方法。
在一项对比研究中，招募了120名患者并随机分为两个亚组，包括传统组（60名患者；24名女性，36名男性；平均年龄：64.35±10.56岁）和专利组（60名患者；28名女性，32名男性；平均年龄：60.15±8.92岁）。收集了所有人口统计学数据，包括年龄、性别、体重指数和CAD相关危险因素（吸烟、糖尿病、高血压），以及技术数据，包括导管数量、手术持续时间、止血压迫时间和临床结果（桡动脉闭塞[RAO]、血肿、出血）。数据采用SPSS 16版进行分析。
我们的研究结果显示，与传统组相比，专利组的RAO发生率显著更低（P = 0.041）。此外，早期闭塞的RAO差异发生率高于晚期闭塞（P = 0.041）。此外，传统组患者中一些因素与闭塞之间存在显著关系（性别[P = 0.038]、年龄[P = 0.031]、糖尿病[P = 0.043]、止血压迫时间[P = 0.036]），专利组中也存在显著关系（年龄[P = 0.009]、高血压[P = 0.035]）。
我们的研究结果表明，与经典方法相比，专利方法中的RAO，尤其是早期类型显著更低；专利止血是最安全的方法，是经典方法的良好替代方法。
