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Early intervention for youth at high risk for bipolar disorder: A multisite randomized trial of family-focused treatment.青少年双相障碍高危人群的早期干预:家庭为中心的治疗多中心随机试验。
Early Interv Psychiatry. 2019 Apr;13(2):208-216. doi: 10.1111/eip.12463. Epub 2017 Aug 4.
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Family-Focused Therapy for Bipolar Disorder: Reflections on 30 Years of Research.双相情感障碍的家庭聚焦治疗:30年研究反思
Fam Process. 2016 Sep;55(3):483-99. doi: 10.1111/famp.12237. Epub 2016 Jul 29.
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Decreases in perceived maternal criticism predict improvement in subthreshold psychotic symptoms in a randomized trial of family-focused therapy for individuals at clinical high risk for psychosis.在一项针对临床高危精神病个体的家庭聚焦治疗随机试验中,感知到的母亲批评减少预示着阈下精神病症状的改善。
J Fam Psychol. 2015 Dec;29(6):945-51. doi: 10.1037/fam0000123. Epub 2015 Jul 13.
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Social skills training and computer-assisted cognitive remediation in schizophrenia.精神分裂症的社交技能训练与计算机辅助认知康复
Schizophr Res. 2015 Mar;162(1-3):35-41. doi: 10.1016/j.schres.2015.01.020. Epub 2015 Jan 29.
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Family-focused treatment for adolescents and young adults at high risk for psychosis: results of a randomized trial.针对有精神病高风险的青少年和青年的家庭聚焦治疗:一项随机试验的结果
J Am Acad Child Adolesc Psychiatry. 2014 Aug;53(8):848-58. doi: 10.1016/j.jaac.2014.04.020. Epub 2014 Jun 2.
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The longitudinal interplay of affective and cognitive empathy within and between adolescents and mothers.青少年及其母亲的情感和认知同理心在内部和之间的纵向相互作用。
Dev Psychol. 2014 Apr;50(4):1219-25. doi: 10.1037/a0035050. Epub 2013 Nov 11.
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A randomized trial of family focused therapy with populations at clinical high risk for psychosis: effects on interactional behavior.针对临床高风险精神病群体的家庭聚焦疗法随机试验:对互动行为的影响
J Consult Clin Psychol. 2014 Feb;82(1):90-101. doi: 10.1037/a0034667. Epub 2013 Nov 4.
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A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry.人类杏仁核-前额叶回路中连接从正性到负性的发展转变。
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Early intervention for symptomatic youth at risk for bipolar disorder: a randomized trial of family-focused therapy.有双相障碍风险症状的青年早期干预:家庭为焦点的治疗的随机试验。
J Am Acad Child Adolesc Psychiatry. 2013 Feb;52(2):121-31. doi: 10.1016/j.jaac.2012.10.007. Epub 2013 Jan 2.
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Brain structural abnormalities at the onset of schizophrenia and bipolar disorder: a meta-analysis of controlled magnetic resonance imaging studies.精神分裂症和双相情感障碍发病时的脑结构异常:对照磁共振成像研究的荟萃分析。
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青少年精神病或双相情感障碍临床高风险家庭沟通。

Family communication with teens at clinical high-risk for psychosis or bipolar disorder.

机构信息

Department of Psychology, Yale University.

Department of Psychiatry and Behavioral Sciences, University of California, Los Angeles School of Medicine.

出版信息

J Fam Psychol. 2018 Jun;32(4):507-516. doi: 10.1037/fam0000393. Epub 2018 Feb 1.

DOI:10.1037/fam0000393
PMID:29389150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5992095/
Abstract

Previous research has found that family problem-solving interactions are more constructive and less contentious when there is a family member with bipolar disorder compared with schizophrenia. The present study extended this research by examining whether family problem-solving interactions differ between clinical high-risk (CHR) stages of each illness. Trained coders applied a behavioral coding system (O'Brien et al., 2014) to problem-solving interactions of parents and their adolescent child, conducted just prior to beginning a randomized trial of family-focused therapy. The CHR for psychosis sample included 58 families with an adolescent with attenuated positive symptoms, brief intermittent psychosis, or genetic risk and functional deterioration; the CHR for bipolar disorder sample included 44 families with an adolescent with "unspecified" bipolar disorder or major depressive disorder and at least one first or second degree relative with bipolar I or II disorder. When controlling for adolescent gender, age, functioning, and parent education, mothers of youth at CHR for psychosis displayed significantly more conflictual and less constructive communication than did mothers of youth at CHR for bipolar disorder. Youth risk classification did not have a significant relationship with youths' or fathers' communication behavior. The family environment among help-seeking adolescents may be more challenging for families with an adolescent at CHR for psychosis compared with bipolar illness. Accordingly, families of adolescents at clinical high-risk for psychosis may benefit from more intensive or focused communication training than is required by families of adolescents at clinical high-risk for bipolar disorder or other mood disorders. (PsycINFO Database Record

摘要

先前的研究发现,与精神分裂症相比,当家庭中有成员患有双相情感障碍时,家庭解决问题的互动会更具建设性,也更少争议。本研究通过检查每种疾病的临床高风险(CHR)阶段是否存在家庭解决问题的互动差异,扩展了这一研究。经过培训的编码员应用一种行为编码系统(O'Brien 等人,2014 年)对父母及其青少年子女的解决问题的互动进行编码,这些互动是在开始家庭为重点的治疗随机试验之前进行的。精神病的 CHR 样本包括 58 个家庭,这些家庭的青少年有减弱的阳性症状、短暂间歇性精神病、或遗传风险和功能恶化;双相情感障碍的 CHR 样本包括 44 个家庭,这些家庭的青少年有“未指定”的双相情感障碍或重性抑郁障碍,并且至少有一个一级或二级亲属患有双相 I 型或 II 型障碍。当控制青少年的性别、年龄、功能和父母教育时,处于精神病 CHR 的青少年的母亲表现出明显更多的冲突和较少的建设性沟通,而处于双相情感障碍 CHR 的青少年的母亲则较少。青少年风险分类与青少年或父亲的沟通行为没有显著关系。与患有双相情感障碍相比,寻求帮助的青少年的家庭环境对于处于精神病 CHR 的青少年的家庭可能更具挑战性。因此,与处于双相情感障碍或其他心境障碍的临床高风险青少年的家庭相比,处于精神病临床高风险的青少年的家庭可能需要更密集或更有针对性的沟通培训。