Bonte J, Janssens J P, Ide P
Eur J Gynaecol Oncol. 1986;7(1):45-50.
In the therapeutic schemes of the hormone-dependent gynecologic cancers, the combined administration of tamoxifen and medroxyprogesterone, generally, scores better results. The highly hormone-dependent tumors (ER+, PgR+) respond very well to a combined, simultaneous treatment. The strictly hormone-dependent (ER+, PgR-) and the potentially hormone-dependent (ER-, PgR-) tumors seem to be most efficiently treated by means of a combined, successive scheme.
在激素依赖性妇科癌症的治疗方案中,通常他莫昔芬与甲羟孕酮联合使用能取得更好的效果。高度激素依赖性肿瘤(雌激素受体阳性、孕激素受体阳性)对联合同步治疗反应良好。严格激素依赖性肿瘤(雌激素受体阳性、孕激素受体阴性)和潜在激素依赖性肿瘤(雌激素受体阴性、孕激素受体阴性)似乎通过联合序贯方案治疗最为有效。