Zhang Xianhong, Zhou Mei, Yin Huaying, Dai Ying, Li Yuwei
Department of Neonatology Department of Primary Healthcare, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.
Medicine (Baltimore). 2017 Dec;96(50):e9207. doi: 10.1097/MD.0000000000009207.
Oral motor assessment is used to identify abnormal sucking patterns which may reflect neurodevelopmental problems in preterm infants, but few studies have focused on moderately and late preterm infants. We enrolled 118 moderately and late preterm infants (mean gestational age, 35.04 weeks; mean birth weight, 2347.59 g) and analyzed the relationship between the Neonatal Oral-Motor Assessment Scale scores of these infants and the Chinese revision of Bayley Scales of Infant Development outcomes at 6 months corrected age. And the infants with abnormal sucking pattern had significantly lower Mental Development Index and Psychomotor Development Index and showed a higher rate of below average scores than control group (P = .003, P = .029, P = .022). The incoordination of suck-swallow-respiration was a risk factor for adverse neurodevelopment (RR = 3.67, 95% CI: 1.42-9.45). These indicate that abnormal sucking patterns in moderately and late preterm infants might provide some predictive value for short-term neurodevelopmental outcomes, but the clinical predictive value for developmental delay need to be determined in a longer term follow-up. This finding may offer a basis for early intervention.
口腔运动评估用于识别可能反映早产儿神经发育问题的异常吸吮模式，但很少有研究关注中度和晚期早产儿。我们纳入了118名中度和晚期早产儿（平均胎龄35.04周；平均出生体重2347.59克），并分析了这些婴儿的新生儿口腔运动评估量表得分与矫正年龄6个月时的中国修订版贝利婴儿发育量表结果之间的关系。吸吮模式异常的婴儿其智力发育指数和心理运动发育指数显著较低，且低于平均得分的比例高于对照组（P = 0.003，P = 0.029，P = 0.022）。吸吮-吞咽-呼吸不协调是神经发育不良的一个危险因素（相对危险度=3.67，95%可信区间：1.42-9.45）。这些表明中度和晚期早产儿的异常吸吮模式可能对短期神经发育结果具有一定的预测价值，但对发育迟缓的临床预测价值需要在更长时间的随访中确定。这一发现可能为早期干预提供依据。
