Kamei Keiko, Matsumoto Ippei, Makutani Yusuke, Kawaguchi Kohei, Matsumoto Masataka, Murase Takaaki, Satoi Shumpei, Nakai Takuya, Kamata Ken, Imai Hajime, Chikugo Takaaki, Takeyama Yoshifumi
Dept. of Surgery, Kindai University Faculty of Medicine.
Gan To Kagaku Ryoho. 2017 Nov;44(12):1191-1193.
We present a case ofa 67-year-old woman with Stage IV pancreatic head cancer with invasion to the superior mesenteric vein and artery, and distant lymph node metastases. The patient received S-1 mono-chemotherapy. After 2 courses of chemotherapy, the tumor marker was decreased to the normal levels, and the tumor size was dramatically reduced with undetectable lymph node metastases on CT. As the disease status was maintained following chemotherapy, the patient underwent subtotal stomach preserving pancreaticoduodenectomy, 8 months after initiation of the chemotherapy. Histopathologically, no cancer cells were found in the main tumor and dissected lymph nodes. Final diagnosis was made with pathological complete response. The patient was alive without recurrence for 10 months after surgery.
我们报告一例67岁女性，患有IV期胰头癌，侵犯肠系膜上静脉和动脉，并伴有远处淋巴结转移。该患者接受了S-1单药化疗。化疗2个疗程后，肿瘤标志物降至正常水平，肿瘤大小显著缩小，CT显示淋巴结转移不可见。由于化疗后疾病状态得以维持，患者在化疗开始8个月后接受了保留胃的胰十二指肠次全切除术。组织病理学检查显示，主肿瘤和清扫的淋巴结中未发现癌细胞。最终诊断为病理完全缓解。患者术后存活10个月，无复发。
