[胃癌腹部淋巴结转移的调强放射治疗经验]

[The Experience of the Intensity Modulated Radiation Therapy for Abdominal Lymph Node Metastases from Gastric Cancer].

作者信息

Wada Noriko, Akamaru Yusuke, Otani Keisuke, Higashiguchi Masaya, Nonoshita Takashi, Nishida Kentaro, Takiuchi Daisuke, Sakata Kazuya, Azama Takashi, Morimoto Osakuni, Ota Hirofumi, Kitada Masashi, Shibata Kunitaka

机构信息

Dept. of Gastroenterological Surgery, Ikeda City Hospital.

出版信息

Gan To Kagaku Ryoho. 2017 Nov;44(12):1583-1585.

PMID:29394709

Abstract

The recurrence ofgastric cancer has a poor prognosis in spite ofsystemic chemotherapy. We report three cases oflocal control ofdisease after the recurrence owing to intensity modulated radiation therapy(IMRT). The first case was a 66-yearsold man. He was received distal gastrectomy after neoadjuvant chemotherapy for advanced gastric cancer. Abdominal lymph node metastases appeared 1 year and 7 months after the surgery. IMRT was performed and he keeps CR for 1 year and 8 months. The second case was a 72-years-old man. He received proximal gastrectomy for early gastric cancer. Abdominal lymph node metastasis appeared 1 year and 9 months after the surgery. IMRT was performed and he keeps CR for 1 year. The third case was a 71-years-old woman. She received distal gastrectomy for advanced gastric cancer. Abdominal lymph node metastasis appeared 2 years after the surgery. IMRT was performed and she keeps CR for 10 months. We experienced longtime CR after IMRT against abdominal lymph node metastasis. IMRT could be one ofthe strategies ofthe comprehensive treatment for the recurrence of gastric cancer.

摘要

尽管进行了全身化疗，胃癌复发的预后仍然很差。我们报告了3例因调强放射治疗（IMRT）使复发后疾病获得局部控制的病例。第一例是一名66岁男性。他在接受新辅助化疗后因进展期胃癌接受了远端胃切除术。术后1年7个月出现腹部淋巴结转移。进行了IMRT，他保持完全缓解（CR）状态1年8个月。第二例是一名72岁男性。他因早期胃癌接受了近端胃切除术。术后1年9个月出现腹部淋巴结转移。进行了IMRT，他保持CR状态1年。第三例是一名71岁女性。她因进展期胃癌接受了远端胃切除术。术后2年出现腹部淋巴结转移。进行了IMRT，她保持CR状态10个月。我们经历了IMRT治疗后针对腹部淋巴结转移的长期CR。IMRT可能是胃癌复发综合治疗的策略之一。