Yamauchi Natsuko, Kido Masahiro, Komatsu Shohei, Tanaka Motofumi, Kinoshita Hisoka, Tsugawa Daisuke, Awazu Masafumi, Ueno Kimihiko, Toyama Hirochika, Terai Sachio, Mukubou Hideyo, Ajiki Tetsuo, Fukumoto Takumi
Dept. of Surgery, Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine.
Gan To Kagaku Ryoho. 2017 Nov;44(12):1717-1719.
We report a case of bilobar multiple hepatocellular carcinoma(HCC)with peritoneal dissemination successfullytreated by dual treatment with reductive surgeryplus percutaneous isolated hepatic perfusion(PIHP). A 73-year-old man had sudden abdominal pain and was diagnosed bilobar multiple HCC through some examinations. The abdominal CT scan demonstrated onlya peritoneal dissemination under the liver. We performed partial hepatectomyof the lateral segment and the Spiegel lobe, and resected a peritoneal dissemination. Subsequently, we underwent PIHP twice. The tumor marker was normalized, and CT images demonstrated complete response according to the RECIST. Dual treatment is considered to be a unique therapeutic modalityfor severe advanced HCC.
我们报告一例双侧多发肝细胞癌（HCC）伴腹膜播散患者，通过减瘤手术联合经皮肝隔离灌注（PIHP）双重治疗成功治愈。一名73岁男性突发腹痛，经多项检查诊断为双侧多发HCC。腹部CT扫描仅显示肝下有腹膜播散。我们对外侧段和斯皮格尔叶进行了部分肝切除术，并切除了一处腹膜播散灶。随后，我们进行了两次PIHP治疗。肿瘤标志物恢复正常，CT图像显示根据实体瘤疗效评价标准（RECIST）达到完全缓解。双重治疗被认为是治疗严重晚期HCC的一种独特治疗方式。
