恙虫病性脑膜炎与急性细菌性脑膜炎及结核性脑膜炎的比较
Comparison of Scrub Typhus Meningitis with Acute Bacterial Meningitis and Tuberculous Meningitis.
作者信息
Kakarlapudi Svas Raju, Chacko Anila, Samuel Prasanna, Verghese Valsan Philip, Rose Winsley
机构信息
Departments of Paediatrics, Christian Medical College, Vellore, Tamil Nadu, India.
Departments of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.
出版信息
Indian Pediatr. 2018 Jan 15;55(1):35-37.
OBJECTIVE
To compare scrub typhus meningitis with bacterial and tuberculous meningitis.
METHODS
Children aged <15 years admitted with meningitis were screened and those who fit criteria for diagnosis of scrub typhus meningitis (n=48), bacterial meningitis (n=44) and tuberculous meningitis (n=31) were included for analysis. Clinical features, investigations and outcomes were compared between the three types of meningitis.
RESULTS
Mean age, duration of fever at presentation, presence of headache and, altered sensorium and presence of hepatomegaly/splenomegaly were statistically significantly different between the groups. Scrub typhus had statistically significant thrombocytopenia, shorter hospital stay and a better neurological and mortality outcome.
CONCLUSION
Sub-acute presentation of meningitis in older age group children, and good outcome is associated with scrub typhus when compared to bacterial and tuberculous meningitis.
目的
比较恙虫病性脑膜炎与细菌性和结核性脑膜炎。
方法
对15岁以下因脑膜炎入院的儿童进行筛查，纳入符合恙虫病性脑膜炎诊断标准的患儿（n = 48）、细菌性脑膜炎患儿（n = 44）和结核性脑膜炎患儿（n = 31）进行分析。比较三种类型脑膜炎的临床特征、检查结果及预后。
结果
各组间的平均年龄、就诊时发热持续时间、头痛的存在情况、意识改变以及肝肿大/脾肿大的存在情况在统计学上有显著差异。恙虫病性脑膜炎有统计学意义的血小板减少、住院时间较短以及较好的神经功能和死亡率结局。
结论
与细菌性和结核性脑膜炎相比，大龄儿童亚急性脑膜炎表现以及良好的预后与恙虫病有关。
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