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经皮腔内冠状动脉成形术治疗亚急性和慢性冠状动脉完全闭塞的早期和晚期结果

Early and late outcome of percutaneous transluminal coronary angioplasty for subacute and chronic total coronary occlusion.

作者信息

DiSciascio G, Vetrovec G W, Cowley M J, Wolfgang T C

出版信息

Am Heart J. 1986 May;111(5):833-9. doi: 10.1016/0002-8703(86)90630-7.

Abstract

Percutaneous transluminal coronary angioplasty (PTCA) for nonacute total coronary occlusion was performed in 46 patients, with a 63% primary success rate (29 of 46 procedures). There were no acute myocardial infarctions and no deaths in the study group. There was no difference in success rate according to vessel dilated, prior myocardial infarction, or lesion morphology. The success rate with occlusions less than 2 weeks' duration was 14 of 19 (74%) vs 15 of 27 (55%) with occlusions greater than 2 weeks' duration (p = NS). There was clinical recurrence in 14 of 29 (48%). Factors predictive of recurrence included a greater residual post-PTCA stenosis of 47 +/- 6% in recurrences vs 31 +/- 3% in nonrecurrences (p less than 0.025), while estimated duration of initial occlusion was 1.1 +/- 0.4 months for recurrences vs 3.1 +/- 1 months for nonrecurrences (p = 0.07). PTCA for total occlusion has a lower success rate and higher recurrence rate than PTCA for nontotal stenoses. Recurrence appears to be related to a higher degree of post-PTCA residual narrowing and to a shorter duration of initial occlusion.

摘要

对46例非急性冠状动脉完全闭塞患者进行了经皮腔内冠状动脉成形术(PTCA),初次成功率为63%(46例手术中有29例成功)。研究组无急性心肌梗死和死亡病例。根据扩张的血管、既往心肌梗死或病变形态,成功率无差异。闭塞时间小于2周的成功率为19例中的14例(74%),而闭塞时间大于2周的成功率为27例中的15例(55%)(p=无统计学意义)。29例中有14例(48%)出现临床复发。复发的预测因素包括PTCA术后残余狭窄程度更高,复发组为47±6%,未复发组为31±3%(p<0.025),而初次闭塞的估计持续时间复发组为1.1±0.4个月,未复发组为3.1±1个月(p=0.07)。与非完全狭窄的PTCA相比,完全闭塞的PTCA成功率更低,复发率更高。复发似乎与PTCA术后更高程度的残余狭窄和更短的初次闭塞持续时间有关。

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