Stegelmeier Bryan L, Davis T Zane
USDA/ARS Poisonous Plant Research Laboratory, 1150 East 1400 North, Logan, UT 84341, USA.
USDA/ARS Poisonous Plant Research Laboratory, 1150 East 1400 North, Logan, UT 84341, USA.
Vet Clin North Am Equine Pract. 2018 Apr;34(1):127-139. doi: 10.1016/j.cveq.2017.11.008. Epub 2018 Feb 4.
Because most poisonings occur by toxin ingestion, the gastrointestinal system is the first exposed and, in most cases, it is exposed to the highest toxin concentrations. Consequently, enterocyte damage is common. However, because many toxins produce organ-specific damage, and enterocyte necrosis is easily confused with autolysis, many gastrointestinal lesions are overlooked or overshadowed by other clinical and pathologic changes. The objective of this work is to review several common toxins and poisonous plants that produce primarily gastrointestinal disease.
由于大多数中毒是通过摄入毒素发生的，胃肠道系统是首先接触到毒素的部位，而且在大多数情况下，它接触到的毒素浓度最高。因此，肠上皮细胞损伤很常见。然而，由于许多毒素会产生器官特异性损伤，且肠上皮细胞坏死容易与自溶混淆，许多胃肠道病变会被其他临床和病理变化所忽视或掩盖。这项工作的目的是回顾几种主要引起胃肠道疾病的常见毒素和有毒植物。
