Khan Mohammad Saud, Khan Zubair, Banglore Bhavana Siddegowda, Alkhoury Ghattas, Murphy Laura, Georgescu Claudiu
Department of Internal Medicine, University of Toledo Medical Center, 3000 Arlington Avenue, Mail Stop 1150, Toledo, Ohio, 43614, USA.
Department of Cardiovascular Medicine, University of Toledo Medical Center, Toledo, Ohio, USA.
J Med Case Rep. 2018 Feb 5;12(1):27. doi: 10.1186/s13256-018-1570-x.
Acute purulent bacterial pericarditis is of rare occurrence in this modern antibiotic era. Primary involvement of the pericardium without evidence of underlying infection elsewhere is even rarer. It is a rapidly progressive infection with high mortality. We present an extremely rare case of acute purulent bacterial pericarditis in an immunocompetent adult patient with no underlying chronic medical conditions.
A 33-year-old previously healthy white man presented with the complaints of chest pain and dyspnea. He was diagnosed as having acute pericarditis and was discharged home on indomethacin. Over a period of 2 weeks, his symptoms worsened gradually and he was readmitted to our hospital. He was found to have large pericardial effusion with cardiac tamponade. An urgent pericardiocentesis was done with drainage of 550 ml of purulent material. Cultures grew Streptococcus intermedius confirming the diagnosis of acute purulent bacterial pericarditis. No other focus of infection was identified on imaging workup suggesting primary infection of the pericardium. His clinical course was complicated by development of constrictive pericarditis for which he underwent surgical pericardiectomy. He received a total of 7 weeks of intravenously administered antibiotics with complete clinical recovery.
Acute purulent bacterial pericarditis, although rare, should always be kept in mind as a possible cause of pericarditis. Early recognition and prompt intervention are important for a successful outcome.
在现代抗生素时代,急性化脓性细菌性心包炎较为罕见。心包原发性受累且无其他部位潜在感染证据的情况更为罕见。这是一种进展迅速的感染,死亡率很高。我们报告一例极为罕见的急性化脓性细菌性心包炎病例,患者为免疫功能正常的成年男性,无潜在慢性疾病。
一名33岁既往健康的白人男性因胸痛和呼吸困难就诊。他被诊断为急性心包炎,出院时服用吲哚美辛。在2周的时间里,他的症状逐渐加重,随后再次入院。检查发现他有大量心包积液并伴有心脏压塞。紧急进行了心包穿刺,抽出550毫升脓性物质。培养结果显示为中间型链球菌,确诊为急性化脓性细菌性心包炎。影像学检查未发现其他感染灶,提示心包原发性感染。他的临床病程因缩窄性心包炎的发展而复杂化,为此他接受了心包切除术。他总共接受了7周的静脉抗生素治疗,临床完全康复。
急性化脓性细菌性心包炎虽然罕见,但作为心包炎的一种可能病因应始终予以考虑。早期识别和及时干预对于取得成功的治疗结果很重要。