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社区获得性肺炎链球菌所致急性化脓性心包炎:一例报告

Acute purulent pericarditis secondary to community-acquired streptococcus pneumonia: A case report.

作者信息

English Kevan, Pick Noelle, Schmitz Allyson

机构信息

Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, United States.

Department of Internal Medicine, University of Nebraska College of Medicine, Omaha, NE 68198, United States.

出版信息

World J Clin Cases. 2025 Sep 16;13(26):107748. doi: 10.12998/wjcc.v13.i26.107748.

Abstract

BACKGROUND

Pericarditis is the inflammation of the pericardial sac due to a variety of stimuli that ultimately trigger a stereotyped immune response. This condition accounts for up to 5% of emergency department visits for nonischemic chest pain in Western Europe and North America. The most common symptoms of clinical presentation are chest pain and shortness of breath with associated unique electrocardiographic changes. Acute pericarditis is generally self-limited. However, some cases may be complicated by either tamponade or a large pericardial effusion, which carries a significant risk of recurrence. Risk factors for acute pericarditis include viral infections, cardiac surgery, and autoimmune disorders. A rarer cause of pericardial inflammation includes pneumonia, which can induce purulent pericarditis that has been increasingly rare since the advent of antibiotics. Purulent pericarditis carries a high fatality rate, especially in the setting of tamponade, and is invariably deadly without the administration of antibiotics. Bedside transthoracic echocardiogram is a quick and helpful method that can aid in the diagnosis and management.

CASE SUMMARY

We present the case of a 62-year-old woman who sought medical attention at the emergency department (ED) due to a 5-day history of chest pain, shortness of breath, and subjective fevers. Laboratory findings in the ED were significant for leukocytosis and elevated erythrocyte sedimentation rate and C-reactive protein. A chest X-ray revealed a new focal density within the left lower lung base, and a bedside point-of-care ultrasound showed a pericardial fluid collection. The patient was subsequently admitted, where she underwent pericardiocentesis. Fluid cultures from drainage grew . She was started on broad-spectrum antibiotics immediately after the procedure. The patient was ultimately discharged in stable condition with cardiology and infectious disease follow-up.

CONCLUSION

This case report emphasizes a unique complication of community-acquired pneumonia. Purulent pericarditis due to occurs intrathoracic spread of the organism to the pericardium. This condition is virtually fatal without the administration of antibiotics. Therefore, in the context of suspected pneumonia and a new pericardial fluid collection on imaging, clinicians should suspect purulent pericarditis until proven otherwise, which requires emergent intervention.

摘要

背景

心包炎是由于多种刺激导致心包囊发生炎症,最终引发一种典型的免疫反应。在西欧和北美,这种疾病占非缺血性胸痛急诊就诊病例的比例高达5%。临床表现最常见的症状是胸痛、呼吸急促以及相关的独特心电图变化。急性心包炎通常为自限性疾病。然而,一些病例可能会并发心包填塞或大量心包积液,存在显著的复发风险。急性心包炎的危险因素包括病毒感染、心脏手术和自身免疫性疾病。心包炎的一种较为罕见的病因是肺炎,肺炎可引发脓性心包炎,自抗生素问世以来,脓性心包炎已愈发少见。脓性心包炎病死率高,尤其是在心包填塞的情况下,若不使用抗生素,必然会导致死亡。床旁经胸超声心动图是一种快速且有用的方法,有助于诊断和治疗。

病例摘要

我们报告一例62岁女性病例,该患者因胸痛、呼吸急促及自觉发热5天前往急诊科就诊。急诊科的实验室检查结果显示白细胞增多、红细胞沉降率和C反应蛋白升高。胸部X线检查显示左下肺底部出现新的局灶性致密影,床旁即时超声检查显示有心包积液。患者随后入院并接受了心包穿刺术。引流液培养结果显示……术后立即开始使用广谱抗生素治疗。患者最终病情稳定出院,并安排了心脏病学和传染病方面的随访。

结论

本病例报告强调了社区获得性肺炎的一种独特并发症。由……引起的脓性心包炎是病原体经胸腔蔓延至心包所致。若不使用抗生素,这种情况几乎是致命的。因此,在怀疑肺炎且影像学检查发现新的心包积液时,临床医生应怀疑脓性心包炎,除非有其他证据证明并非如此,而这需要紧急干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0165/12336907/27254879380f/wjcc-13-26-107748-g001.jpg

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