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朗格汉斯细胞组织细胞增多症作为儿童背痛的罕见病因:一例报告及文献复习

Langerhans cell histiocytosis as an unusual cause of back pain in a child: A case report and review of literature.

作者信息

Balachandran Hemaswetha, Sneha Latha M, Menon Gopinath, Scott Julius

机构信息

Department of Pediatrics, Sri Ramachandra University, Chennai, Tamil Nadu, India.

Department of Pediatrics, Division of Pediatric Hemato Oncology, Sri Ramachandra University, Chennai, Tamil Nadu, India.

出版信息

J Craniovertebr Junction Spine. 2017 Oct-Dec;8(4):384-386. doi: 10.4103/jcvjs.JCVJS_105_17.

Abstract

Low back pain in children and adolescents are usually attributed to mechanical causes and faulty positions. Although most of them are self-limiting, physicians should be aware of the red flag signs that warrant complete evaluation to rule out malignant causes of back pain. As delay in the diagnosis of vertebral lytic lesion may have sequelae in the growing children, pain disproportionate to the signs should have low threshold levels for evaluation. We report a case of 6-year-old boy who presented with worsening back pain. Initially evaluated for tuberculosis spine, he was diagnosed to have Langerhans cell histiocytosis of spine. He improved symptomatically with chemotherapy and spine orthosis and is in complete remission now.

摘要

儿童和青少年的腰痛通常归因于机械性原因和不良姿势。尽管其中大多数是自限性的,但医生应注意那些警示体征,这些体征需要进行全面评估以排除背痛的恶性原因。由于椎体溶解性病变诊断的延迟可能会对正在生长的儿童产生后遗症,对于与体征不相称的疼痛,评估的阈值应较低。我们报告一例6岁男孩,他出现了逐渐加重的背痛。最初因脊柱结核接受评估,他被诊断为脊柱朗格汉斯细胞组织细胞增多症。他通过化疗和脊柱矫形器症状得到改善,目前处于完全缓解状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae5/5763601/4d2d9acd36f3/JCVJS-8-384-g001.jpg

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