Ho Vivian Wm, Romano Vito, Steger Bernhard, Kaye Stephen B
Department of Corneal and External Eye Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Department of Eye and Vision Science, University of Liverpool, Liverpool, United Kingdom.
J Ophthalmic Vis Res. 2018 Jan-Mar;13(1):72-74. doi: 10.4103/jovr.jovr_40_16.
To report two cases of spontaneous Descemet's membrane detachment (DMD) and dehiscence following penetrating keratoplasty (PK).
Spontaneous DMD or Descemet's membrane (DM) dehiscence following PK is a rare occurrence. Here, we describe two cases of such an occurrence following PK arising from the graft-host interface. A possible causative relation between DMD/dehiscence and DM-stromal interface attachment is suggested.
DMD and dehiscence after PK can be explained by the peripheral thinning of DM and possible changes to the recently characterized anchoring zone of interwoven collagen fibers and proteoglycans at the Descemet-stroma interface.
报告两例穿透性角膜移植术（PK）后发生的自发性后弹力层脱离（DMD）和裂开病例。
PK术后自发性DMD或后弹力层（DM）裂开是一种罕见的情况。在此，我们描述了两例发生在移植体与宿主界面的PK术后此类情况。提示了DMD/裂开与DM-基质界面附着之间可能存在的因果关系。
PK术后的DMD和裂开可以通过DM的周边变薄以及后弹力层-基质界面处最近所描述的交织胶原纤维和蛋白聚糖锚定区的可能变化来解释。
