Lin Chao-Zhan, Xie Si-Min, Zhu Chen-Chen, Bairu Zeren-Dawa, Kangsa Suolang-Qimei, Zhu Dun
Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou 510405, PR China.
Tibet College of Tibetan Medicines, Lasa 850000, PR China.
J Pharm Anal. 2013 Dec;3(6):447-451. doi: 10.1016/j.jpha.2013.06.002. Epub 2013 Jul 6.
A HPLC-ELSD method was developed and validated for simultaneous determination of five Hetisane-type diterpenoid alkaloids in a Tibetan traditional herbal medicine, "" (), using a Kromasil C column (250 mm×4.6 mm, 5 μm) with the mobile phase consisting of acetonitrile and 0.1% triethylamine in gradient (detected by evaporative light scattering detector). The linear ranges of five compounds were determined and method validation was evaluated completely. The established method is rapid and accurate with high repeatability, and can be applied for the quality control of .
Zotero 插件
