Yazıcıoğlu Alkın, Yekeler Erdal, Yazıcı Ülkü, Aydın Ertan, Taştepe İrfan, Karaoğlanoğlu Nurettin
Clinic of Chest Surgery and Lung Transplantation, Türkiye High Specialization Training and Research Hospital, Ankara, Turkey.
Clinic of Chest Surgery, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Turk Thorac J. 2016 Oct;17(4):148-152. doi: 10.5152/TurkThoracJ.2016.002. Epub 2016 Oct 1.
The objective was to describe changing patterns of etiological factors and treatment modalities for massive hemoptysis.
From January 2008-December 2012, the medical records of 58 massive hemoptysis patients were reviewed.
Fifty-eight patients, 44 were men (75.9%) and 14 were women (24.1%), with a mean age of 51.4 years (range= 19-84 years), were divided into three groups; surgical management (n= 37, 63.8%), conservative management (n= 14, 24.1%) and bronchial artery embolization (n= 6, 10.4%). One case (1.7%) had combined treatment modality; bronchial artery embolization was followed by surgical resection. Anatomical lung resections were the most preferred resection type in the surgical management group (n= 34, 91.9%). The most common etiological factor was bronchiectasis (n= 19, 32.8%); followed by bronchial cancer (n= 14, 24.1%). The duration of hospitalization in the surgical management group was 11.4 days (range= 4-24); whereas in the bronchial artery embolization group, hospitalization was only four days (range= 2-7) (p< 0.01). Prolonged air leak (n= 7; 18.9%) was the most common complication in the surgical management group.
We emphasize that bronchiectasis was leading cause of massive hemoptysis. Surgical treatment remains the definitive therapy in the management of massive hemoptysis with decreased mortality rates over decades; whereas bronchial artery embolization is an effective therapeutic tool.
描述大咯血病因及治疗方式的变化模式。
回顾2008年1月至2012年12月期间58例大咯血患者的病历。
58例患者中,男性44例(75.9%),女性14例(24.1%),平均年龄51.4岁(范围19 - 84岁),分为三组:手术治疗组(n = 37,63.8%)、保守治疗组(n = 14,24.1%)和支气管动脉栓塞组(n = 6,10.4%)。1例(1.7%)采用联合治疗方式,即先行支气管动脉栓塞,随后行手术切除。手术治疗组中,解剖性肺切除是最常用的切除方式(n = 34,91.9%)。最常见的病因是支气管扩张(n = 19,32.8%),其次是支气管癌(n = 14,24.1%)。手术治疗组的住院时间为11.4天(范围4 - 24天);而支气管动脉栓塞组的住院时间仅为4天(范围2 - 7天)(p < 0.01)。手术治疗组最常见的并发症是持续性漏气(n = 7;18.9%)。
我们强调支气管扩张是大咯血的主要原因。手术治疗仍然是大咯血治疗的决定性方法,几十年来死亡率有所下降;而支气管动脉栓塞是一种有效的治疗手段。