Ong Thun-How, Eng Philip
Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Outram Road, Singapore169608, Singapore.
Intensive Care Med. 2003 Feb;29(2):317-20. doi: 10.1007/s00134-002-1553-6. Epub 2002 Nov 2.
Massive hemoptysis can cause airway or hemodynamic compromise requiring intensive care. We reviewed the management and outcome of this group of patients in our institution.
Retrospective analysis.
Medical intensive care unit (MICU) in a tertiary care hospital.
Patients (29 patients with 31 episodes) who were admitted to the MICU for massive hemoptysis (greater than 300 ml/24 h or requiring intubation) between August 1997 and April 2001.
Patients were intensively monitored and electively intubated if there was danger of airway compromise. Fiberoptic bronchoscopy was performed to assess the site of bleeding and patients had bronchial artery embolisation if deemed suitable. Patients in whom bleeding could not be controlled were referred for emergency surgery.
In 26/31 (84%) episodes, patients required intubation. Bronchoscopy was more helpful in localising the bleeding (site of bleeding identified in 90%) than chest X-ray alone (identified site of bleeding in 64%). Bleeding was stopped with medical therapy in 8/31 (26%) patient; 16/31(51%) patients were successfully treated with embolisation. Only four (13%) patients went for emergency surgery, of whom one died. Overall in-hospital mortality was 4/31 patients (13%). Over a 2 year follow-up, 6/27 (22%) survivors had recurrent hemoptysis and another 4 (15%) died of unrelated causes.
Intensive care and monitoring with endotracheal intubation, when necessary, are useful in massive hemoptysis. Bronchoscopy should be performed to help localise the bleeding site. Embolisation is a suitable first-line treatment for massive hemoptysis, reserving emergency surgery for cases where the above measures are insufficient to control bleeding.
大量咯血可导致气道或血流动力学障碍,需要重症监护。我们回顾了我院这组患者的治疗及预后情况。
回顾性分析。
一家三级医院的内科重症监护病房(MICU)。
1997年8月至2001年4月期间因大量咯血(超过300毫升/24小时或需要插管)入住MICU的患者(29例患者,共31次发作)。
对患者进行密切监测,如有气道受损危险则选择性插管。进行纤维支气管镜检查以评估出血部位,若认为合适则对患者进行支气管动脉栓塞术。出血无法控制的患者被转至急诊手术。
在31次发作中的26次(84%),患者需要插管。支气管镜检查在确定出血部位方面比单纯胸部X线检查更有帮助(90%的病例确定了出血部位,而胸部X线检查单独确定出血部位的比例为64%)。31例患者中有8例(26%)通过药物治疗止血;16例(51%)患者通过栓塞术成功治疗。只有4例(13%)患者接受了急诊手术,其中1例死亡。总体住院死亡率为31例患者中的4例(13%)。在2年的随访中,27例幸存者中有6例(22%)复发咯血,另有4例(15%)死于无关原因。
必要时进行重症监护和气管插管监测对大量咯血患者有用。应进行支气管镜检查以帮助确定出血部位。栓塞术是大量咯血合适的一线治疗方法,对于上述措施不足以控制出血的病例保留急诊手术。