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扩大经鼻内镜入路治疗鞍上颅咽管瘤

Extended Endoscopic Endonasal Approach for Suprasellar Craniopharyngioma.

作者信息

Locatelli D, Pozzi F, Agresta G, Padovan S, Karligkiotis A, Castelnuovo P

机构信息

Department of Neurosurgery, University of Insubria - Ospedale di Circolo Fondazione Macchi, Varese, Italy.

Department of Neurosurgery, ASST Sette Laghi, Ospedale di Circolo Fondazione Macchi, Varese, Italy.

出版信息

J Neurol Surg B Skull Base. 2018 Feb;79(2):S196-S198. doi: 10.1055/s-0038-1623529. Epub 2018 Jan 18.

DOI:10.1055/s-0038-1623529
PMID:29404249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5796833/
Abstract

We illustrate a suprasellar craniopharyngiomas treated with an extended endoscopic endonasal approach (EEEA).  Case report of a 43-year-old male affected by cerebral lesion located in suprasellar region involving the third ventricle and compressing the neurovascular structures, causing an anterosuperior dislocation of the chiasma. There is a complete disruption of the pituitary stalk that can explain the clinical finding of partial anterior hypopituitarism and hyperprolactinemia. The lesion is characterized by a solid and cystic component. Considering the absence of lateral extension and the suprasellar location of the lesion, an EEEA is preferred.  University Hospital "Ospedale di Circolo," Department of Neurosurgery, Varese, Italy.  Neurosurgical and ENT Skull Base Team.  A bilateral parasagittal approach is performed using a four-hand technique. The first step of the surgery is the preparation of the Hadad's flap. The approach is extended to the planum sphenoidalis to expose the suprasellar region. The lesion is completely removed employing also an ultrasound aspirator. Skull base reconstruction is performed with three-layer technique: graft of fat tissue, fascia lata, and nasoseptal flap.  No postoperative complications occurred. In the post-op, the patient presents a panhypopituitarism and an improvement in neurological status. The visual deficit remains stable. Post-op magnetic resonance imaging at 1 year documents the complete absence of pathological contrast enhancement.  EEEA is a feasible approach in treating craniopharyngioma with suprasellar extension. The advantages include optimal visualization, good resection rate, and absence of brain retraction. The link to the video can be found at: https://youtu.be/IYm-8P1jbBo .

摘要

我们展示了一例采用扩大经鼻内镜入路(EEEA)治疗的鞍上颅咽管瘤。

病例报告

一名43岁男性,脑部病变位于鞍上区域,累及第三脑室并压迫神经血管结构,导致视交叉前上方移位。垂体柄完全中断,这可以解释部分垂体前叶功能减退和高泌乳素血症的临床表现。病变具有实性和囊性成分。考虑到病变无外侧扩展且位于鞍上,首选EEEA。

意大利瓦雷泽“Circolo医院”大学医院神经外科。

神经外科和耳鼻喉科颅底团队。

采用双手操作技术进行双侧矢状旁入路。手术的第一步是制备哈达德皮瓣。入路扩展至蝶骨平台以暴露鞍上区域。还使用超声吸引器将病变完全切除。采用三层技术进行颅底重建:脂肪组织移植、阔筋膜移植和鼻中隔皮瓣移植。

未发生术后并发症。术后,患者出现全垂体功能减退,神经状态有所改善。视力缺损保持稳定。术后1年的磁共振成像显示完全没有病理性对比增强。

EEEA是治疗鞍上扩展型颅咽管瘤的一种可行方法。其优点包括视野最佳、切除率高且无需脑牵拉。视频链接可在:https://youtu.be/IYm-8P1jbBo 找到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8a/5796833/a4f834d73855/10-1055-s-0038-1623529-i170179ov-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8a/5796833/b9637fef1af3/10-1055-s-0038-1623529-i170179ov-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8a/5796833/a4f834d73855/10-1055-s-0038-1623529-i170179ov-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8a/5796833/b9637fef1af3/10-1055-s-0038-1623529-i170179ov-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8a/5796833/a4f834d73855/10-1055-s-0038-1623529-i170179ov-2.jpg

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