Maes Karen A, Hersberger Kurt E, Lampert Markus L
Pharmaceutical Care Research Group, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Institute of Hospital Pharmacy, Solothurner Spitäler, Olten, Switzerland.
Int J Clin Pharm. 2018 Apr;40(2):335-340. doi: 10.1007/s11096-018-0595-y. Epub 2018 Feb 5.
Background While dispensing prescribed medicines, pharmacists frequently encounter technical and clinical problems that require a pharmaceutical intervention. Objective To describe the pharmaceutical interventions performed by community pharmacists while dispensing prescribed medicines and to investigate, in-depth, the patient-reported problems with the prescribed medicines that triggered pharmaceutical interventions. Method Twenty-one pharmacists each collected 30 prescriptions requiring a pharmaceutical intervention on five selected days within a five-week period. All pharmaceutical interventions were classified using the PharmDISC system. Results Of all 430 pharmaceutical interventions, 286 (66.5%) pharmaceutical interventions had a clinical cause and 144 (33.5%) pharmaceutical interventions a technical cause. Pharmacists mainly intervened to substitute a drug (n = 132, 30.7%), adjust a dose (n = 57, 13.3%), and clarify/complete information (n = 48, 11.2%). A total of 243 (56.5%) pharmaceutical interventions resulted in a change of the prescription. The implementation rate of pharmaceutical interventions reached 88.6%. Altogether, patient-reported problems triggered 99 (23.0%) pharmaceutical interventions. In 15 (15.2%) of these PIs, contact with the prescriber was necessary, whereas 61 (84.8%) PIs only involved the pharmacist. Conclusion While dispensing prescribed medicines, pharmacists performed individualised pharmaceutical interventions to solve or prevent drug-related problems. That almost a quarter of all pharmaceutical interventions triggered by patient-reported problems highlights the importance of direct patient-pharmacist interaction when dispensing prescribed medicines.
背景 在配发处方药时，药剂师经常遇到需要药物干预的技术和临床问题。目的 描述社区药剂师在配发处方药时进行的药物干预，并深入调查引发药物干预的患者报告的处方药问题。方法 21名药剂师在五周内的五个选定日期，每人收集30份需要药物干预的处方。所有药物干预均使用PharmDISC系统进行分类。结果 在所有430次药物干预中，286次（66.5%）药物干预有临床原因，144次（33.5%）药物干预有技术原因。药剂师主要进行药物替代干预（n = 132，30.7%）、调整剂量干预（n = 57，13.3%）以及澄清/完善信息干预（n = 48，11.2%）。共有243次（56.5%）药物干预导致了处方变更。药物干预的实施率达到88.6%。患者报告的问题共引发了99次（23.0%）药物干预。在这些药物干预中，15次（15.2%）需要与开处方者联系，而61次（84.8%）药物干预仅涉及药剂师。结论 在配发处方药时，药剂师进行个性化的药物干预以解决或预防与药物相关的问题。患者报告的问题引发了近四分之一的药物干预，这凸显了在配发处方药时患者与药剂师直接互动的重要性。
