Tasaka Yuichi, Yasunaga Daiki, Tanaka Mamoru, Tanaka Akihiro, Asakawa Takashige, Horio Ikuo, Miyauchi Yoshiro, Araki Hiroaki
Ehime University Hospital, 454 Shistukawa, Toon, Ehime, Japan.
Ehime Society of Hospital Pharmacists, 454 Shistukawa, Toon, Ehime, Japan.
Int J Clin Pharm. 2016 Apr;38(2):321-9. doi: 10.1007/s11096-015-0245-6. Epub 2016 Jan 8.
Pharmaceutical interventions by community and hospital pharmacists can improve medication safety and result in financial savings. Their effect has not been fully explored in Japan.
To evaluate the economic and safety contributions of various pharmaceutical interventions by community and hospital pharmacists in Japan.
Two hospitals and eight community pharmacies in Ehime Prefecture, Japan, in 2014-2015.
Pharmacists entered data about pharmaceutical interventions via the internet, and the data were divided into 11 types of interventions. The economic impact was estimated based on the rate of avoidance of serious adverse drug reactions and the monetary cost of these reactions in the Japanese compensation system. The cost saving from adjusting prescriptions to take account of unused prescription drugs was calculated using drug prices from the national health insurance scheme. Main
The number of pharmaceutical interventions and their economic impact. RESULTS The total cost savings from 500 to 509 pharmaceutical interventions by community and hospital pharmacists were US$207,126.6 and US$592,840, respectively. Community pharmacists mainly intervened to correct prescription errors. They also adjusted 135 prescriptions to take account of unused prescription drugs. This potentially improved patients' adherence and contributed to effective use of medication. Pharmaceutical interventions by hospital pharmacists facilitated avoidance of 10 serious adverse drug reactions, and included 42 transvenous antimicrobial therapy interventions, 88 interventions in cancer chemotherapy, and 47 monitoring recommendations. Hospital pharmacists helped improve patients' quality of life using more aggressive interventions besides correcting prescription errors. Over half of pharmaceutical interventions by community and hospital pharmacists contributed to avoidance of adverse drug reactions.
These results suggest the importance of pharmaceutical interventions by both community and hospital pharmacists in reducing increasing medical expenses and contributing to safety and effectiveness of medication. They also suggest that community and hospital pharmacists have different roles.
社区和医院药剂师的药学干预可提高用药安全性并节省费用。在日本，其效果尚未得到充分研究。
评估日本社区和医院药剂师进行的各种药学干预的经济和安全贡献。
2014 - 2015年日本爱媛县的两家医院和八家社区药房。
药剂师通过互联网输入药学干预数据，这些数据被分为11种干预类型。根据严重药物不良反应的避免率以及日本赔偿系统中这些反应的货币成本来估计经济影响。利用国家健康保险计划的药品价格计算因调整处方以考虑未使用的处方药而节省的费用。
药学干预的数量及其经济影响。
社区和医院药剂师进行的500至509次药学干预分别节省了207,126.6美元和592,840美元的总成本。社区药剂师主要干预纠正处方错误。他们还调整了135张处方以考虑未使用的处方药。这可能提高了患者的依从性并有助于药物的有效使用。医院药剂师的药学干预促成避免了10起严重药物不良反应，包括42次经静脉抗菌治疗干预、88次癌症化疗干预和47次监测建议。除了纠正处方错误外，医院药剂师通过更积极的干预帮助提高了患者的生活质量。社区和医院药剂师超过一半的药学干预有助于避免药物不良反应。
这些结果表明社区和医院药剂师的药学干预在降低不断增加的医疗费用以及促进用药安全和有效性方面的重要性。它们还表明社区和医院药剂师具有不同的作用。
