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在军事人群中,提示磁共振成像(MRI)转诊的非对称听力损失:重新定义听力学标准。

Asymmetric Hearing Loss Prompting MRI Referral in a Military Population: Redefining Audiometric Criteria.

机构信息

1 Department of Otolaryngology, Tripler Army Medical Center, Honolulu, Hawaii, USA.

2 Department of Radiology, Tripler Army Medical Center, Honolulu, Hawaii, USA.

出版信息

Otolaryngol Head Neck Surg. 2018 Apr;158(4):695-701. doi: 10.1177/0194599818756300. Epub 2018 Feb 6.

Abstract

Objective To reevaluate asymmetric sensorineural hearing loss (ASNHL) criteria used to justify magnetic resonance imaging (MRI) in the evaluation of retrocochlear tumors in a military population. Study Design Retrospective case-control study. Setting Tertiary care military medical center. Subjects and Methods Patients with military service and a history of ASNHL prompting referral for MRI, with or without retrocochlear tumors, were compared between 2005 and 2016. Predictor variables included pure tone ASNHL, speech audiometry, and a history of noise exposure. Logistic regression models for hearing asymmetries were performed, and receiver operator curves were used to calculate sensitivity and specificity. Results Thirty-eight retrocochlear tumors were identified. The MRI diagnosis rate for patients with ASHNL was 0.85%. Patients with tumors were slightly older (42 vs 37 years, P = .021) and had less noise exposure (47% vs 85%, P < .001). A sensitivity of 0.83 and a specificity of 0.58 were calculated for asymmetries ≥10 dB at 2000 Hz without adjusting for noise exposure. Instituting this imaging threshold would have reduced the number of MRI scans by half while missing 16% of tumors. Conclusion The tumor diagnosis rate among those undergoing MRI for ASNHL is low in the military population, likely because service-related noise exposure commonly causes ASNHL. Optimal MRI referral criteria should conserve resources while balancing the risks of over- and underdiagnosis. For those with a history of military service, an asymmetry ≥10 dB at 2000 Hz among patients meeting current ANSHL referral criteria is most predictive of a retrocochlear tumor.

摘要

目的 重新评估用于评估军事人群中迷路后肿瘤的磁共振成像(MRI)的不对称感音神经性听力损失(ASNHL)标准。

研究设计 回顾性病例对照研究。

设置 三级保健军事医疗中心。

患者和方法 2005 年至 2016 年间,比较了有军事服务史和 ASNHL 病史的患者,这些患者因 ASNHL 而转诊进行 MRI,无论是否存在迷路后肿瘤。预测变量包括纯音 ASNHL、言语测听和噪声暴露史。对听力不对称的逻辑回归模型进行了分析,并使用接收器操作曲线计算了灵敏度和特异性。

结果 共发现 38 例迷路后肿瘤。MRI 对有 ASHNL 的患者的诊断率为 0.85%。有肿瘤的患者年龄稍大(42 岁比 37 岁,P =.021),噪声暴露较少(47%比 85%,P <.001)。未调整噪声暴露时,2000 Hz 处不对称性≥10 dB 的灵敏度为 0.83,特异性为 0.58。如果实施这种成像阈值,将使 MRI 扫描数量减少一半,同时漏诊 16%的肿瘤。

结论 在军事人群中,因 ASNHL 而行 MRI 的患者中肿瘤的诊断率较低,这可能是因为与服役相关的噪声暴露通常会导致 ASNHL。最佳的 MRI 转诊标准应在平衡过度诊断和漏诊风险的同时节约资源。对于有军事服务史的患者,当前 ASNHL 转诊标准中符合条件的患者在 2000 Hz 处的不对称性≥10 dB 最能预测迷路后肿瘤。

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