Mello Gustavo W, Riet-Correa Franklin, Batista Maria C, Carvalho Ciro J, Dias Alexandre C, Franklin Fabio L, Silva Silvana M, Dias Alex
Universidade Estadual do Piauí, Campus Professor Alexandre Alves de Oliveira s/n, Parnaíba, Brasil (Mello).
Hospital Veterinário, Centro de Saúde e Tecnologia Rural, Universidade Federal de Campina Grande, Campus de Patos, Patos, Brasil (Riet-Correa).
J Vet Diagn Invest. 2018 May;30(3):476-478. doi: 10.1177/1040638718757581. Epub 2018 Feb 6.
Farmers in the State of Piauí in northeastern Brazil reported nervous signs in ruminants and donkeys after ingestion of Brunfelsia uniflora at the start of the rainy season when the plant is flowering. Leaves of the plant, collected at the start or at the end of the rainy season, were administered in single doses of 5-20 g/kg body weight to 8 sheep and 3 donkeys. Two sheep and 1 donkey that ingested 10 g/kg of the plant in November at the start of the rainy season, when the plant was flowering, developed severe convulsions and diarrhea. One sheep was euthanized and autopsied, and no significant lesions were found. The other sheep and the donkey recovered. Four sheep and one donkey that ingested 10 or 20 g/kg of leaves collected in April, at the end of the rainy season, did not show clinical signs. One donkey that ingested 5 g/kg of leaves collected in November developed diarrhea and recovered. These results demonstrate the toxicity of B. uniflora for livestock and suggest that the plant is toxic at these doses only during the start of the rainy season.
巴西东北部皮奥伊州的农民报告称，在雨季开始、该植物开花时，反刍动物和驴在摄入单花鸳鸯茉莉后出现了神经症状。在雨季开始或结束时采集的该植物叶片，以5 - 20克/千克体重的单剂量喂给8只绵羊和3头驴。11月雨季开始、植物开花时，2只绵羊和1头驴摄入了10克/千克的该植物，出现了严重惊厥和腹泻。对1只绵羊实施安乐死并进行解剖，未发现明显病变。其他绵羊和驴康复。4只绵羊和1头驴在4月雨季结束时摄入了10或20克/千克采集的叶片，未表现出临床症状。1头驴在11月摄入了5克/千克采集的叶片，出现腹泻后康复。这些结果证明了单花鸳鸯茉莉对家畜有毒，并表明该植物仅在雨季开始时的这些剂量下具有毒性。
