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肠延长术的长期效果:避免了多少移植,针对哪些患者?

Long-term results of surgery for bowel lengthening: how many transplants are avoided, for which patients?

机构信息

Pediatric Surgery Service, La Paz University Hospital, Madrid, Spain.

出版信息

Curr Opin Organ Transplant. 2018 Apr;23(2):207-211. doi: 10.1097/MOT.0000000000000508.

Abstract

PURPOSE OF REVIEW

One of the biggest successes of intestinal rehabilitation programs is that more patients achieve enteral autonomy without transplantation. Many factors are responsible of this accomplishment including new parenteral formulas, better catheter management, surgical management, and the experience of the teams. The purpose of this review is to analyze recent published papers regarding intestinal lengthening procedures trying to find out how many transplantations are avoided and for which patients.

RECENT FINDINGS

A trend towards performing less intestinal transplants has been identified in the last years. The general improvement of intestinal rehabilitation accounts for this step forward. However, the role of intestinal lengthening has not been clarified.

SUMMARY

Surgical techniques for autologous reconstructive surgery are not limited to bowel lengthening. Longitudinal intestinal lengthening and tailoring and serial transverse enteroplasty offered good results in terms of intestinal adaptation, long-term survival, and subsequent need of intestinal transplantation. In recent series, less than one quarter of patients who underwent intestinal lengthening required salvage intestinal transplantation.

摘要

目的综述

肠道康复计划最大的成功之一是更多的患者在不进行移植的情况下实现了肠内自主。许多因素促成了这一成就,包括新的肠外配方、更好的导管管理、手术管理以及团队的经验。本综述的目的是分析最近发表的关于肠延长术的论文,试图找出避免了多少移植以及为哪些患者避免了移植。

最近发现

近年来,肠移植的数量呈下降趋势。肠道康复的总体改善是这一进展的原因。然而,肠延长的作用尚未得到明确。

总结

用于自体重建手术的外科技术不仅限于肠延长。肠延长和裁剪以及序贯横结肠切开术在肠适应、长期生存和随后需要肠移植方面取得了良好的效果。在最近的系列研究中,不到四分之一接受肠延长术的患者需要进行挽救性肠移植。

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