Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada; Division of Emergency Medicine, the Department of Medicine, and the Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Can J Cardiol. 2018 Feb;34(2):125-131. doi: 10.1016/j.cjca.2017.11.009. Epub 2017 Nov 22.
Atrial fibrillation is a frequent reason for presentation to an emergency department (ED), and the number of these visits are increasing. This creates an opportunity to improve the suboptimal rate of oral anticoagulation (OAC) use in patients with atrial fibrillation who are at high risk of stroke. However, there are very few data on whether OAC initiation in the ED, compared with referral to the longitudinal health care provider to initiate it, results in better long-term use. Moreover, for ethical and medicolegal reasons, physicians who initiate a chronic medication are obliged to reassess the patient at a later date, to check for medication side effects and the need for dose adjustment. More research is needed to determine whether OAC should be prescribed in the ED, by a physician who will never see the patient again. Patients who are cardioverted in the ED might be an exception, secondary to the increased risk of stroke after cardioversion. If ED OAC prescribing is associated with better outcomes, these results must be placed into context with the care and outcomes of the other patients in the ED. If there is a net benefit, the findings should be disseminated to practicing emergency physicians, preferably via emergency physician opinion leaders. An implementation science-based approach, which addresses the barriers to ED OAC prescribing (eg, the competing demands of running an ED and lack of guaranteed follow-up care after discharge from an ED), should be used to support prescribing of OAC in the ED. Potential solutions are described.
心房颤动是急诊科就诊的常见原因,就诊人数正在增加。这为提高高卒中风险心房颤动患者的口服抗凝剂(OAC)使用率提供了机会。然而,关于在急诊科启动 OAC 与将患者转诊至长期医疗保健提供者启动 OAC 相比,是否能更好地长期使用 OAC,几乎没有数据。此外,出于伦理和医疗法律原因,启动慢性药物治疗的医生有义务在以后的日期重新评估患者,以检查药物副作用和剂量调整的需要。需要更多的研究来确定是否应该在急诊科由以后再也不会见到患者的医生开具 OAC。电复律后患者可能是一个例外,因为电复律后卒中风险增加。如果 ED OAC 处方与更好的结果相关,那么这些结果必须与急诊科其他患者的护理和结果联系起来。如果有净收益,应通过急诊医师意见领袖等方式将这些发现传播给执业急诊医师。应采用基于实施科学的方法来解决 ED OAC 处方的障碍(例如,急诊科的运作需求以及从急诊科出院后缺乏保证的后续护理),以支持在急诊科开具 OAC。描述了潜在的解决方案。