由苄青霉素引起且与阿莫西林有交叉反应的药物超敏反应伴嗜酸性粒细胞增多和系统症状（DRESS）综合征。 - Suppr

DRESS Syndrome due to benzylpenicillin with cross-reactivity to amoxicillin.

作者信息

Watts Timothy J, Li Philip H, Haque Rubaiyat

机构信息

Department of Adult Allergy, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

Department of Adult Allergy, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; Division of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong.

出版信息

J Allergy Clin Immunol Pract. 2018 Sep-Oct;6(5):1766-1768. doi: 10.1016/j.jaip.2018.01.011. Epub 2018 Jan 31.

DOI:10.1016/j.jaip.2018.01.011

PMID:29408014

Abstract

摘要

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DRESS Syndrome due to benzylpenicillin with cross-reactivity to amoxicillin.由苄青霉素引起且与阿莫西林有交叉反应的药物超敏反应伴嗜酸性粒细胞增多和系统症状（DRESS）综合征。

J Allergy Clin Immunol Pract. 2018 Sep-Oct;6(5):1766-1768. doi: 10.1016/j.jaip.2018.01.011. Epub 2018 Jan 31.

Drug reaction with eosinophilia and systemic symptoms from ceftriaxone confirmed by positive patch test: An immunohistochemical study.斑贴试验阳性证实头孢曲松所致药物反应伴嗜酸性粒细胞增多和全身症状：一项免疫组织化学研究

J Allergy Clin Immunol Pract. 2017 May-Jun;5(3):808-810. doi: 10.1016/j.jaip.2016.10.009. Epub 2016 Dec 4.

Amoxicillin challenge without penicillin skin testing in evaluation of penicillin allergy in a cohort of Marine recruits.在一组海军新兵中，不进行青霉素皮肤试验而采用阿莫西林激发试验来评估青霉素过敏情况。

J Allergy Clin Immunol Pract. 2017 May-Jun;5(3):813-815. doi: 10.1016/j.jaip.2017.01.023. Epub 2017 Mar 21.

Drug allergy: in vitro cross-allergenicity between amoxicillin and benzyl penicillin.药物过敏：阿莫西林与苄青霉素之间的体外交叉致敏性。

Biomedicine. 1979 Jul;30(3):168-72.

Penicillin skin testing without minor determinate mixture and amoxicillin challenge in the Appalachian region.阿巴拉契亚地区无次要决定簇混合物的青霉素皮肤试验及阿莫西林激发试验

Ann Allergy Asthma Immunol. 2018 Feb;120(2):217-219. doi: 10.1016/j.anai.2017.11.018.

Clinical usefulness of patch and challenge tests in the diagnosis of cell-mediated allergy to betalactams.斑贴试验和激发试验在β-内酰胺类药物细胞介导性过敏诊断中的临床应用价值

Ann Allergy Asthma Immunol. 1999 Sep;83(3):257-66. doi: 10.1016/S1081-1206(10)62650-6.

The Addition of Benzylpenicillin Does Not Increase the Skin Test Sensitivity Obtained With Classic β-Lactam Determinants.添加苄青霉素不会增加经典β-内酰胺决定簇所获得的皮肤试验敏感性。

J Investig Allergol Clin Immunol. 2016;26(1):52-4.

Diagnosis of penicillin, amoxicillin, and cephalosporin allergy: reliability of examination assessed by skin testing and oral challenge.青霉素、阿莫西林和头孢菌素过敏的诊断：通过皮肤试验和口服激发试验评估检查的可靠性。

J Pediatr. 1998 Jan;132(1):137-43. doi: 10.1016/s0022-3476(98)70499-8.

Onset of penicillin rashes: relation between type of penicillin administered and type of immune reactivity.青霉素皮疹的发作：所用青霉素类型与免疫反应类型之间的关系。

Allergy. 1986 Jan;41(1):75-8. doi: 10.1111/j.1398-9995.1986.tb00279.x.

The cross-reactivity and immunology of beta-lactam antibiotics.β-内酰胺类抗生素的交叉反应性和免疫学

Drug Saf. 1994 Apr;10(4):318-27. doi: 10.2165/00002018-199410040-00006.

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Delayed-type drug eruption to phenazopyridine (pyridium) confirmed with patch testing.斑贴试验证实的对非那吡啶（吡啶）的迟发型药物疹。

Asia Pac Allergy. 2022 Jan 25;12(1):e10. doi: 10.5415/apallergy.2022.12.e10. eCollection 2022 Jan.

Myocarditis and Drug Rash With Eosinophilia and Systemic Symptoms Syndrome: A Deadly Combination.心肌炎与伴有嗜酸性粒细胞增多和全身症状的药物疹综合征：一种致命组合。

Cureus. 2021 Feb 22;13(2):e13496. doi: 10.7759/cureus.13496.

Cross With Caution: Antibiotic Cross-Reactivity and Co-Reactivity Patterns in Severe Cutaneous Adverse Reactions.慎重交叉：严重皮肤不良反应中的抗生素交叉反应和共同反应模式。

Front Immunol. 2021 Feb 25;12:601954. doi: 10.3389/fimmu.2021.601954. eCollection 2021.

Delabeling Delayed Drug Hypersensitivity: How Far Can You Safely Go?去标签化延迟药物过敏：你能走多远？

J Allergy Clin Immunol Pract. 2020 Oct;8(9):2878-2895.e6. doi: 10.1016/j.jaip.2020.07.005.

Antibacterial antibiotic-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a literature review.抗菌抗生素引起的伴嗜酸性粒细胞增多和全身症状（DRESS）综合征：文献综述。

Eur J Clin Pharmacol. 2021 Mar;77(3):275-289. doi: 10.1007/s00228-020-03005-9. Epub 2020 Oct 6.

Safety of cephalosporins in penicillin class severe delayed hypersensitivity reactions.头孢菌素在青霉素类严重迟发型超敏反应中的安全性。

J Allergy Clin Immunol Pract. 2020 Mar;8(3):1142-1146.e4. doi: 10.1016/j.jaip.2019.10.005. Epub 2019 Oct 31.

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DRESS Syndrome due to benzylpenicillin with cross-reactivity to amoxicillin.

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