Joo So Young, Hong A Ram, Lee Boung Chul, Choi Jae Hyuk, Seo Cheong Hoon
Department of Rehabilitation Medicine, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Republic of Korea.
Department of Neuropsychiatry, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Republic of Korea.
Burns. 2018 Jun;44(4):834-840. doi: 10.1016/j.burns.2017.12.012. Epub 2018 Feb 4.
Heart rate variability (HRV) is a noninvasive method used to quantify fluctuations in the time interval between normal heart beats. The purpose of this study was to compare the autonomic nervous system functioning of patients with burns to healthy participants after their burn scars had been re-epithelialized.
The authors prospectively performed 24-h HRV monitoring in 60 patients with electrical burns, those with other major burns, those with other minor burns, and 10 healthy participants. Analysis of HRV in the time and frequency domain was performed.
The difference in sympathetic nerve measures (standard deviation of NN intervals [SDNN], total power [TP] and a low frequency [LF] band) and parasympathetic nerve measures (Root mean square successive difference [RMSSD], the number of interval differences of successive NN intervals greater than 50ms [NN50], the percentage of differences between following RR intervals greater than 50ms [pNN50] and a high frequency [HF] band) in patients with burns was significantly decreased during the daytime and the nighttime. the difference in parasympathetic nerve measures were more significantly decreased during the nighttime compared with measures of HRV in healthy participants. The groups of other burns showed significantly lower HRV than the electrical burn group indexed by a very low frequency (VLF) measure and TP during the daytime.
We hypothesized that HRV is a surrogate for autonomic nervous system dysfunction in patients with burns. The patients with burns were observed a sympathetic predominance during daytime and a decreased parasympathetic activity during nighttime. These results of patients with other major burns were more predominant compared with the results of patients with other groups.
心率变异性（HRV）是一种用于量化正常心跳之间时间间隔波动的非侵入性方法。本研究的目的是比较烧伤患者在烧伤瘢痕重新上皮化后与健康参与者的自主神经系统功能。
作者前瞻性地对60例电烧伤患者、其他重度烧伤患者、其他轻度烧伤患者以及10名健康参与者进行了24小时HRV监测。对HRV进行了时域和频域分析。
烧伤患者交感神经指标（NN间期标准差[SDNN]、总功率[TP]和低频[LF]频段）和副交感神经指标（连续NN间期的均方根差[RMSSD]、连续NN间期差值大于50ms的数量[NN50]、RR间期后续差值大于50ms的百分比[pNN50]和高频[HF]频段）在白天和夜间均显著降低。与健康参与者的HRV指标相比，副交感神经指标在夜间的降低更为显著。在白天，其他烧伤组的HRV以极低频（VLF）测量值和TP为指标，显著低于电烧伤组。
我们假设HRV是烧伤患者自主神经系统功能障碍的替代指标。观察到烧伤患者白天交感神经占优势，夜间副交感神经活动降低。与其他组患者的结果相比，其他重度烧伤患者的这些结果更为明显。
