Maruyama Yuta, Shigemura Tomonari, Aoyama Koki, Nagano Noriyuki, Nakazawa Yozo
Shinshu Ueda Medical Center, Department of Pediatrics, Ueda, Japan.
Shinshu University, School of Medicine, Department of Pediatrics, Matsumoto, Japan.
Braz J Infect Dis. 2018 Jan-Feb;22(1):60-62. doi: 10.1016/j.bjid.2017.10.008. Epub 2018 Feb 2.
Herein we report the case of a 10-year-old boy with an autosomal mosaic mutation who developed bacteremia. The causative agent was identified as Moraxella osloensis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene sequencing. In the pediatric population, there have been 13 case reports of infection attributed to M. osloensis and this is the fifth reported case of pediatric bacteremia due to M. osloensis. After Moraxella species infection was confirmed, the patient recovered with appropriate antimicrobial therapy. It is important to consider that M. osloensis can cause serious infections, such as bacteremia, in otherwise healthy children.
在此,我们报告一例患有常染色体嵌合突变的10岁男孩发生菌血症的病例。通过基质辅助激光解吸/电离飞行时间质谱和16S rRNA基因测序,确定病原体为奥斯陆莫拉菌。在儿科人群中,已有13例归因于奥斯陆莫拉菌感染的病例报告,这是第五例报告的因奥斯陆莫拉菌导致的儿科菌血症病例。在确认莫拉菌属感染后,患者通过适当的抗菌治疗得以康复。重要的是要认识到,奥斯陆莫拉菌可在原本健康的儿童中引起严重感染,如菌血症。