Balogun James A, Adeleke Nurudeen A, Salami Ayodeji O, Odebode Timothy O
Division of Neurosurgery, Department of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria; Department of Neurosurgery, University College Hospital, Ibadan, Nigeria; Division of Neurosurgery, Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Division of Neurosurgery, Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
World Neurosurg. 2018 Apr;112:153-157. doi: 10.1016/j.wneu.2018.01.128. Epub 2018 Jan 31.
Epidermoid tumors are rare, benign slow-growing congenital tumors, most frequently located in the cerebellopontine angle of the intracranial cavity. They usually grow to a large size before patients become symptomatic. Although these tumors are amenable to surgery, their adherence to neurovascular structures poses a surgical challenge that results in subtotal resection, thus increasing the risk of recurrence.
We report 2 adult patients whose imaging studies revealed epidermoid tumors located in the cerebellar vermis, an uncommon site for such tumors. The patients presented with variable symptomatology. We highlight the imaging features and challenges of surgery. Both patients had good outcomes, with resolution of symptoms and neurologic deficits.
A safe complete excision of epidermoid tumor and its capsule is possible with a good understanding of their clinical and radiologic features and a high index of suspicion. To the best of our knowledge, this is the first report of cerebellar vermian epidermoid tumors from sub-Saharan Africa.
表皮样肿瘤是罕见的、良性生长缓慢的先天性肿瘤，最常位于颅内腔的桥小脑角。它们通常在患者出现症状之前长到很大的尺寸。尽管这些肿瘤适合手术治疗，但它们与神经血管结构的粘连给手术带来了挑战，导致次全切除，从而增加了复发风险。
我们报告了2例成年患者，其影像学检查显示表皮样肿瘤位于小脑蚓部，这是此类肿瘤不常见的部位。患者表现出不同的症状。我们强调了影像学特征和手术挑战。两名患者均取得了良好的结果，症状和神经功能缺损均得到缓解。
在充分了解表皮样肿瘤的临床和放射学特征并保持高度怀疑的情况下，安全完整地切除肿瘤及其包膜是可能的。据我们所知，这是撒哈拉以南非洲地区关于小脑蚓部表皮样肿瘤的首例报告。
