Gupta Rupesh, Gupta Sweta, Das Ranjit Kumar, Basu Supriya, Agrawal Vishnu
Department of Urology, R.G. Kar Medical College and Hospital, Kolkata, India.
Department of Obstetrics and Gynaecology, R.G. Kar Medical College and Hospital, Kolkata, India.
Cent European J Urol. 2017;70(4):400-404. doi: 10.5173/ceju.2017.1379. Epub 2017 Sep 18.
Several minimally invasive approaches are available for the treatment of bladder stones, with each having its own advantages and disadvantages. We devised a new technique to overcome a few limitations of conventional techniques and compared its efficacy with conventional percutaneous cystolithotripsy (PCCL) technique.
This was a randomized, open-label, prospective, controlled study conducted from July 2015 to December 2016 that included 62 patients with bladder calculus of ≥2 cm in size. Patients were randomly assigned into two groups. Patients from Group 1 were treated with new a technique using a transurethral nephroscope via resectoscope outer sheath and patients from Group 2 were treated with conventional PCCL.
Overall, the mean (SD) age was 53.3 (11.4) years and 49.9 (12.8) years for Group 1 and 2, respectively; and stone size was 3.2 (0.8) and 3.2 (0.7), respectively. Operative time was similar in both groups (32.7 [8.7] versus 34.3 [7.0]; P = 0.428). The length of hospital stay was higher in Group 2 (2.1 [0.4]) as compared to Group 1 (1.2 [0.5]) (P = 0.000). Stones were completely cleared in all patients.Group 2 patients required more analgesics and had more complications like hematuria and wound infection.
Results showed that cystolithotripsy with nephroscope via resectoscope sheath is an alternative to the conventional PCCL techniques as the new technique was associated with lesser complications, better cosmetic outcome and minimal analgesic requirement.
目前有几种微创方法可用于治疗膀胱结石,每种方法都有其自身的优缺点。我们设计了一种新技术以克服传统技术的一些局限性,并将其疗效与传统经皮膀胱碎石术(PCCL)技术进行比较。
这是一项于2015年7月至2016年12月进行的随机、开放标签、前瞻性对照研究,纳入了62例膀胱结石大小≥2 cm的患者。患者被随机分为两组。第1组患者采用经尿道肾镜经电切镜外鞘的新技术进行治疗,第2组患者采用传统PCCL进行治疗。
总体而言,第1组和第2组的平均(标准差)年龄分别为53.3(11.4)岁和49.9(12.8)岁;结石大小分别为3.2(0.8)和3.2(0.7)。两组的手术时间相似(32.7 [8.7]对34.3 [7.0];P = 0.428)。第2组的住院时间(2.1 [0.4])高于第1组(1.2 [0.5])(P = 0.000)。所有患者的结石均完全清除。第2组患者需要更多的镇痛药,且有更多并发症,如血尿和伤口感染。
结果表明,经电切镜鞘用肾镜进行膀胱碎石术是传统PCCL技术的一种替代方法,因为新技术并发症较少、美容效果更好且镇痛药需求最少。