一例免疫球蛋白G与乳酸脱氢酶结合，导致酶活性丧失和异常同工酶谱的病例。
A case of immunoglobulin G conjugated with lactate dehydrogenase, producing both loss of enzyme activity and an abnormal isoenzyme pattern.
作者信息
Sudo K, Maekawa M, Watanabe H, Matsumoto K, Mori Y, Sasaki T, Kanno T
出版信息
Clin Chem. 1986 Jul;32(7):1420-2.
PMID:2941184
Abstract
We present a patient with an inhibitor of lactate dehydrogenase (LD; EC 1.1.1.27) in serum, who had pericarditis and myocardial hypertrophy. The patient's LD activity in serum was low and the LD isoenzyme pattern was abnormal. The relative molecular mass of this abnormal LD-IgG complex was approximately 490 000. The patient's IgG reacted with all five LD isoenzymes.
摘要
我们报告一例血清中存在乳酸脱氢酶（LD；EC 1.1.1.27）抑制物的患者，该患者患有心包炎和心肌肥厚。患者血清中的LD活性较低，且LD同工酶谱异常。这种异常的LD-IgG复合物的相对分子质量约为490000。患者的IgG与所有五种LD同工酶均发生反应。
Zotero 插件