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老年人的昼夜节律性睡眠-觉醒障碍

Circadian Rhythm Sleep-Wake Disorders in Older Adults.

作者信息

Kim Jee Hyun, Duffy Jeanne F

机构信息

Department of Neurology, Dankook University College of Medicine, Dankook University Hospital, Manghyang-ro 201, Dongnam-gu, Cheonan, Chungnam 31116, Republic of Korea; Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, 221 Longwood Avenue, BLI438, Boston, MA 02115, USA; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA.

Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, 221 Longwood Avenue, BLI438, Boston, MA 02115, USA; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA.

出版信息

Sleep Med Clin. 2018 Mar;13(1):39-50. doi: 10.1016/j.jsmc.2017.09.004. Epub 2017 Nov 27.

Abstract

The timing, duration, and consolidation of sleep result from the interaction of the circadian timing system with a sleep-wake homeostatic process. When aligned and functioning optimally, this allows wakefulness throughout the day and a long consolidated sleep episode at night. Mismatch between the desired timing of sleep and the ability to fall and remain asleep is a hallmark of the circadian rhythm sleep-wake disorders. This article discusses changes in circadian regulation of sleep with aging; how age influences the prevalence, diagnosis, and treatment of circadian rhythm sleep-wake disorders; and how neurologic diseases in older patients affect circadian rhythms and sleep.

摘要

睡眠的时间、时长和巩固是由昼夜节律系统与睡眠-觉醒稳态过程相互作用产生的。当两者协调且功能最佳时,就能使人白天保持清醒,夜间获得长时间的巩固睡眠。期望的睡眠时间与入睡及保持睡眠能力之间的不匹配是昼夜节律性睡眠-觉醒障碍的一个标志。本文讨论了随着年龄增长睡眠昼夜节律调节的变化;年龄如何影响昼夜节律性睡眠-觉醒障碍的患病率、诊断和治疗;以及老年患者的神经系统疾病如何影响昼夜节律和睡眠。

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