Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 300 Pasteur Drive, Alway M211, Stanford, CA 94305, USA.
Department of Clinical Nutrition, Stanford Health Care, Stanford, 300 Pasteur Drive, Palo Alto, CA 94305, USA.
Gastroenterol Clin North Am. 2018 Mar;47(1):155-177. doi: 10.1016/j.gtc.2017.09.007. Epub 2017 Dec 7.
Nutritional strategies have been explored as primary or adjunct therapies for inflammatory bowel disease (IBD). Exclusive enteral nutrition is effective for the induction of remission in Crohn disease and is recommended as a first-line therapy for children. Dietary strategies focus on adjusting the ratio of consumed nutrients that are proinflammatory or antiinflammatory. Treatments with dietary supplements focus on the antiinflammatory effects of the individual supplements (eg, curcumin, omega-3 fatty acids, vitamin D) or their positive effects on the intestinal microbiome (eg, prebiotics, probiotics). This article discusses the role of diets and dietary supplements in the treatment of IBD.
营养策略已被探索作为炎症性肠病 (IBD) 的主要或辅助治疗方法。肠内营养是有效的诱导缓解克罗恩病,被推荐为儿童的一线治疗方法。饮食策略侧重于调整消耗的营养素的比例,这些营养素具有促炎或抗炎作用。饮食补充剂的治疗方法侧重于个别补充剂的抗炎作用(例如,姜黄素、ω-3 脂肪酸、维生素 D)或它们对肠道微生物组的积极影响(例如,益生元、益生菌)。本文讨论了饮食和饮食补充剂在治疗 IBD 中的作用。