进正餐时 NONO 斑点：肝脏适应食物的时机。
Mealtime Is NONO Speckled: Timing Hepatic Adaptation to Food.
机构信息
Faculté de Médecine Nord, Aix Marseille Université, CNRS, CRN2M-UMR7286, Marseille, France.
Charité Universitätsmedizin Berlin, Laboratory of Chronobiology, 10117 Berlin, Germany.
出版信息
Cell Metab. 2018 Feb 6;27(2):268-270. doi: 10.1016/j.cmet.2018.01.009.
PMID:29414680
Abstract
You are what you eat; but when you eat also seems to be important for a healthy metabolism. In this issue of Cell Metabolism, Benegiamo et al. (2018) uncover a mechanism by which the RNA-binding protein NONO promotes the time-of-day-dependent expression of key metabolic genes at a post-transcriptional level in response to nutrition.
摘要
你吃什么就是什么；但进食时间似乎对健康的新陈代谢也很重要。在本期《细胞代谢》中，Benegiamo 等人（2018 年）揭示了 RNA 结合蛋白 NONO 通过一种机制，在响应营养的情况下，在转录后水平促进关键代谢基因的昼夜节律表达。
Zotero 插件