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一名溃疡性结肠炎患者的苏萨克综合征

Síndrome de Susac en un paciente con colitis ulcerosa.

作者信息

Rodríguez-Martínez José Antonio, Echarri-Piudo Ana

机构信息

Departamento de Imagenología Diagnóstica y Terapéutica, Hospital General Dr. Manuel Gea González, Secretaría de Salud, Ciudad de México, México.

Departamento de Gastroenterología, Hospital Arquitecto Marcide, Servicio Gallego de Salud, Ferrol, La Coruña, España.

出版信息

Gac Med Mex. 2017;153(7):924-927. doi: 10.24875/GMM.17002798.

Abstract

The Susac's syndrome is a rare disorder that was first described in 1979 and is characterized by a classic triad consisting in encephalopathy, visual impairment and sensorineural hearing loss. However, the etiology of the disease is still unclear. We report the case of a 29-year-old with ulcerative colitis treated with mercaptopurine, six months before to her admission started with personality changes attributed to symptoms of depression who subsequently present neurological symptoms characteristic of Susac's Syndrome. In the literature there is no clear association between inflammatory bowel disease and Susac's -syndrome, but this case is presented in order to emphasize the simultaneous presentation of these two diseases with a tendency to vasospasm and an autoimmune pathogenesis.

摘要

苏萨克综合征是一种罕见疾病,于1979年首次被描述,其特征为典型的三联征,包括脑病、视力损害和感音神经性听力损失。然而,该疾病的病因仍不明确。我们报告一例29岁溃疡性结肠炎患者,在入院前六个月接受巯嘌呤治疗,起初出现归因于抑郁症状的人格改变,随后出现苏萨克综合征的典型神经症状。文献中炎症性肠病与苏萨克综合征之间没有明确关联,但呈现此病例是为了强调这两种疾病同时出现且有血管痉挛倾向和自身免疫发病机制。

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