Martín Raúl Álvarez-San
Centro Médico ABC, Ciudad de México, México.
Gac Med Mex. 2017;153(7):946-951. doi: 10.24875/GMM.17002973.
Marshall R. Urist was an American orthopedic surgeon who worked in University of California at Los Angeles. His scientific work about bone formation brought to medical science the discovery of a bone growth inductor substance known as bone morphogenetic protein in 1965. The protein today is a recombinant genetically produced substance which helps to regenerate connective tissues and stimulates non specialized cells to transform in to osteoblastic cell lineage. This biographical document about Urist reviews his life, career, classic scientific papers and those landmark contributions to medical science.
马歇尔·R·尤里斯特是一位美国骨科医生,曾在加利福尼亚大学洛杉矶分校工作。他在1965年关于骨形成的科学研究为医学带来了一项发现,即一种名为骨形态发生蛋白的骨生长诱导物质。如今,这种蛋白质是一种通过基因重组生产的物质,有助于结缔组织再生,并刺激非特化细胞转化为成骨细胞谱系。这份关于尤里斯特的传记性文档回顾了他的人生、职业生涯、经典科学论文以及他对医学的那些具有里程碑意义的贡献。