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墨尔本一家城市医院的快速反应小组对潜在阿片类药物毒性及纳洛酮反应的评估。

Assessment of potential opioid toxicity and response to naloxone by rapid response teams at an urban Melbourne hospital.

作者信息

Gunasekaran Bharathy, Weil Jennifer, Whelan Tom, Santamaria John, Boughey Mark

机构信息

Department of Medicine, St Vincent's Hospital, Melbourne, Victoria, Australia.

Centre for Palliative Care, St Vincent's Hospital, Melbourne, Victoria, Australia.

出版信息

Intern Med J. 2018 Feb;48(2):198-200. doi: 10.1111/imj.13692.

Abstract

Opioid prescriptions have significantly increased in recent years and are used for a wide variety of indications. Electronic medical records of 45 patients who received naloxone by a rapid response team over an 18-month period were retrospectively reviewed. This study found inconsistencies in the management of possible opioid toxicity with variation in the total naloxone dose and number of doses administered. This highlights the importance of a standardised protocol for recognition and management of opioid overdose.

摘要

近年来,阿片类药物的处方量显著增加,且用于多种适应症。对45例在18个月期间由快速反应小组给予纳洛酮治疗的患者的电子病历进行了回顾性分析。本研究发现,在可能的阿片类药物中毒管理方面存在不一致之处,纳洛酮总剂量和给药次数存在差异。这凸显了制定阿片类药物过量识别和管理标准化方案的重要性。

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