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两种不同手术入路联合腰椎椎间融合内固定治疗单节段腰椎疾病的病例对照研究

[Case control study on two different surgical approaches combined fixation with lumbar interbody fusion for the treatment of single segmental lumbar vertebra diseases].

作者信息

Zeng Zhong-You, Yan Wei-Feng, Song Yong-Xing, Mao Ke-Ya, Ji Jian-Fei, Zhang Jian-Qiao, Wu Peng, Pei Fei, Song Guo-Hao, Han Jian-Fu, Yu Wei

机构信息

The Second Department of Orthopaedics, Hospital of Zhejiang General Corps of Chinese People's Armed Police Forces, Jiaxing 314000, Zhejiang, China;

出版信息

Zhongguo Gu Shang. 2017 May 25;30(5):417-425. doi: 10.3969/j.issn.1003-0034.2017.05.006.

Abstract

OBJECTIVE

To discuss the advantages and disadvantages of two different surgical approaches combined fixation with lumbar interbody fusion in treating single segmental lumbar vertebra diseases.

METHODS

The clinical data of 86 patients with single segmental lumbar vertebra diseases treated from June 2011 to June 2013 was retrospectively analyzed. There were 33 males and 53 females, aged from 28 to 76 years old with an average of 53.0 years. Among them, there were 39 cases of lumbar disc degeneration, 22 cases of lumbar disc herniation complicated with spinal canal stenosis, 9 cases of huge lumbar disc herniation and 16 cases of lumbar degenerative spondylolisthesis (Meyerding degree I ). Lesion sites contained L3, 4 in 5 cases, L4, 5 in 70 cases and L5S1 in 11 cases. All the patients were treated with internal fixation and lumbar interbody fusion with 45 cases by midline incision approach (median incision group) and the other 41 cases by channel-assisted by muscle-splitting approach(channel group). Incision length, operation time, intraoperative bleeding and postoperative drainage were recorded in two groups. Visual analogue scale(VAS) was used to assess lumbar incision pain 72 h after operation. Depended on imaging results to compare the changes of the disc space height in lesion in preoperative, postoperative and final follow-up, the coronal and sagittal Cobb angle in preoperative and final follow-up, the area of multifidus and the degree of multifidus fat deposition before and after operation between two groups. Loosening or fragmentation of internal fixation, displacement of intervertebral cage and interbody fusion were observed in each group. Japanese Orthopedic Association (JOA) scoring system was used to evaluate the function before operation and at the final follow-up.

RESULTS

The channel group was superior to the median incision group in incision length and postoperative drainage while the median incision group was less than the channel group in the operation time and intraoperative bleeding. The average VAS score of lumbar incision 72 h after operation was 1.50 points in median incision group and 0.97 points in channel group, and there was significant difference between two groups(<0.05). No incision infection was found, but there were 4 cases of incisional epidermal necrosis, 1 case of incision healed badness, and 3 cases of nerve injury in channel group. The incidence of cacothesis of pedicle screw were 5.0% and 3.6% in median incision group and channel group respectively, and there was no significant difference between two groups(>0.05). The incidence of cacothesis of translaminar facet screw were 6.6% and 12.2% in median incision group and channel group respectively, and there was significant difference between two groups(<0.05). All the patients were followed up for 12 to 36 months with a mean of 22.8 months. The changes of disc space height had statistical difference between preoperative and postoperative(<0.05) in all patients, but there was no significant difference between postoperative and final follow-up(>0.05), however, there was no significant difference 3 days after operation and final follow-up between two groups(>0.05). At final follow-up, coronal and sagittal Cobb angle were obviously improved in all patients(<0.05), but there was no significant difference between two groups(>0.05). One year after operation, the area of multifidus in median incision group was (789.00±143.15) mm² less than preoperative(1 066.00±173.55) mm² (<0.05), and in channel group, was(992.00±156.75) mm² at 1 year after operation and(1 063.00±172.13) mm² preoperatively, there was no significant difference between them(>0.05), however, there was significant difference one year after operation between two groups (<0.05) . About the degree of multifidus fat deposition, there was significant difference between one year after operation and preoperation in median incision group (<0.05), but there was no significant difference between one year after operation and preoperation in channel group (>0.05), and there was significant difference at one year after operation between two groups(<0.05). During the follow-up period, neither pedicle screw and/or translaminar facet screw loosening, displacement or fragmentation nor displacement of intervertebral cage were found. The lumbar interbody fusion rate was 95.6% in median incision group and was 95.1% in channel group, and there was no significant difference between two groups(>0.05). No obvious adjacent segmental degeneration was observed in fixed position. JOA score in median incision group was significantly increased from 8-16 points (average: 12.77±2.56) preoperative to 21-29 points (average: 25.20±2.43) at final follow-up(<0.05); and in channel group was significantly increased from 8-16 points (average: 12.64±2.37) preoperative to 23-29 points(average: 26.7±1.82) at final follow-up(<0.05); there was also significant difference between two groups at final follow-up.

CONCLUSIONS

Compared to the median incision approach, unilateral pedicle screw combined with contralateral translaminar facet screw fixation using channel-assisted by muscle-splitting approach has advantages of small incision, less trauma, fast recovery and so on. However, it also has shortages such as high surgical complications incidence, especially in cases that.

摘要

目的

探讨两种不同手术入路联合腰椎椎间融合内固定术治疗单节段腰椎疾病的优缺点。

方法

回顾性分析2011年6月至2013年6月收治的86例单节段腰椎疾病患者的临床资料。其中男33例,女53例,年龄28~76岁,平均53.0岁。其中腰椎间盘退变39例,腰椎间盘突出症合并椎管狭窄22例,巨大腰椎间盘突出症9例,腰椎退变性滑脱(Meyerding Ⅰ度)16例。病变节段:L3、4 5例,L4、5 70例,L5S1 11例。所有患者均行内固定及腰椎椎间融合术,经正中切口入路45例(正中切口组),经肌间隙通道辅助入路41例(通道组)。记录两组手术切口长度、手术时间、术中出血量及术后引流量。采用视觉模拟评分法(VAS)评估术后72 h腰部切口疼痛情况。根据影像学结果比较两组术前、术后及末次随访时病变节段椎间隙高度变化,术前及末次随访时冠状面和矢状面Cobb角,术前及术后多裂肌面积及多裂肌脂肪沉积程度。观察两组内固定松动或断裂、椎间融合器移位及椎间融合情况。采用日本骨科学会(JOA)评分系统评估术前及末次随访时的功能。

结果

通道组在切口长度和术后引流量方面优于正中切口组,而正中切口组在手术时间和术中出血量方面少于通道组。术后72 h腰部切口VAS平均评分,正中切口组为1.50分,通道组为0.97分,两组比较差异有统计学意义(<0.05)。两组均无切口感染,但通道组有4例切口表皮坏死,1例切口愈合不良,3例神经损伤。正中切口组和通道组椎弓根螺钉置入不当发生率分别为5.0%和3.6%,两组比较差异无统计学意义(>0.05)。正中切口组和通道组经椎板关节突螺钉置入不当发生率分别为6.6%和12.2%,两组比较差异有统计学意义(<0.05)。所有患者均随访12~36个月,平均22.8个月。所有患者术前与术后椎间隙高度变化有统计学差异(<0.05),但术后与末次随访比较差异无统计学意义(>0.05),两组术后3 d与末次随访比较差异无统计学意义(>0.05)。末次随访时,所有患者冠状面和矢状面Cobb角均明显改善(<0.05),但两组比较差异无统计学意义(>0.05)。术后1年,正中切口组多裂肌面积(789.00±

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