Romo Muñoz M I, Martínez de Aragón A, Núñez Cerezo V, Udaondo C, Sellers M, Barrena S, De Ceano M, López Santamaría M, Martínez Martínez L
Servicio de Cirugía Pediátrica. Hospital Universitario Infantil La Paz. Madrid.
Estudiante. Universidad Autónoma de Madrid.
Cir Pediatr. 2018 Feb 1;31(1):34-38.
Hirschsprung's-associated enterocolitis (HAEC) is a live-threatening complication that remains badly understood. Our objective is to identify the risk factors related to the development of HAEC in the cohort of patients with Hirschsprung's disease (HD) treated in our center.
We reviewed the patients treated for HD between 2000 and 2016. Ninety four patients were included, and the clinical details related to the disease were evaluated. Our primary outcome measure was the development of HAEC. Relative risks are presented with 95% confidence intervals.
Twenty seven patients out of the ninety four (28.7%) suffered HAEC. None of them died from this complication. The extended aganglionosis, the need of a preoperative stoma, a transabdominal surgery and the diagnosis before the age of 7.2 months were related to a higher risk of suffering HAEC.
HAEC remains a common complication in patients suffering from HD, especially those with complex forms. The identification of the risk factors could result in a better control of the HAEC, which lead to a faster diagnosis and treatment, reducing the morbi-mortality related to HAEC.
先天性巨结肠相关小肠结肠炎（HAEC）是一种危及生命的并发症，目前仍了解不足。我们的目的是在本中心接受治疗的先天性巨结肠（HD）患者队列中，确定与HAEC发生相关的危险因素。
我们回顾了2000年至2016年间接受HD治疗的患者。纳入94例患者，并评估了与该疾病相关的临床细节。我们的主要结局指标是HAEC的发生。相对风险以95%置信区间表示。
94例患者中有27例（28.7%）发生了HAEC。他们中无人死于该并发症。病变肠段无神经节细胞范围扩大、术前需要造口、经腹手术以及在7.2月龄前确诊与发生HAEC的较高风险相关。
HAEC仍然是HD患者，尤其是复杂型患者中的常见并发症。识别危险因素可更好地控制HAEC，从而实现更快的诊断和治疗，降低与HAEC相关的病残率和死亡率。
