当乙酰胆碱解锁皮层中的反馈抑制。

When Acetylcholine Unlocks Feedback Inhibition in Cortex.

机构信息

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

出版信息

Neuron. 2018 Feb 7;97(3):481-484. doi: 10.1016/j.neuron.2018.01.042.

DOI:10.1016/j.neuron.2018.01.042

PMID:29420929

Abstract

Acetylcholine promotes cognitive function through the regulation of cortical circuits. In this issue of Neuron, Urban-Ciecko et al. (2018) demonstrate how this neuromodulator can rapidly boost synapses from pyramidal to somatostatin neurons, unlocking a new computational ability in the cortical microcircuitry.

摘要

乙酰胆碱通过调节皮质回路促进认知功能。在本期《神经元》杂志中，Urban-Ciecko 等人（2018 年）展示了这种神经调质如何能快速增强从锥体神经元到生长抑素神经元的突触，从而为皮质微电路解锁一种新的计算能力。