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年轻人对使用快速芬太尼检测条的意愿较高。

High willingness to use rapid fentanyl test strips among young adults who use drugs.

机构信息

Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S-121-2, Providence, RI, 02912, USA.

School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Harm Reduct J. 2018 Feb 8;15(1):7. doi: 10.1186/s12954-018-0213-2.

Abstract

BACKGROUND

Synthetic opioid overdose mortality among young adults has risen more than 300% in the USA since 2013, primarily due to the contamination of heroin and other drugs with illicitly manufactured fentanyl. Rapid test strips, which can be used to detect the presence of fentanyl in drug samples (before use) or urine (after use), may help inform people about their exposure risk. The purpose of this study was to determine whether young adults who use drugs were willing to use rapid test strips as a harm reduction intervention to prevent overdose. We hypothesized that those who had ever overdosed would be more willing to use the test strips.

METHODS

We recruited a convenience sample of young adults who use drugs in Rhode Island from May to September 2017. Eligible participants (aged 18 to 35 with past 30-day drug use) completed an interviewer-administered survey. The survey assessed participant's socio-demographic and behavioral characteristics, overdose risk, as well as suspected fentanyl exposure, and willingness to use take-home rapid test strips to detect fentanyl contamination in drugs or urine. Participants were then trained to use the test strips and were given ten to take home.

RESULTS

Among 93 eligible participants, the mean age was 27 years (SD = 4.8), 56% (n = 52) of participants were male, and 56% (n = 52) were white. Over one third (n = 34, 37%) had a prior overdose. The vast majority (n = 86, 92%) of participants wanted to know if there was fentanyl in their drug supply prior to their use. Sixty-five (70%) participants reported concern that their drugs were contaminated with fentanyl. After the brief training, nearly all participants (n = 88, 95%) reported that they planned to use the test strips.

CONCLUSIONS

More than 90% of participants reported willingness to use rapid test strips regardless of having ever overdosed, suggesting that rapid fentanyl testing is an acceptable harm reduction intervention among young people who use drugs in Rhode Island. Study follow-up is ongoing to determine whether, how, and under what circumstances participants used the rapid test strips and if a positive result contributed to changes in overdose risk behavior.

摘要

背景

自 2013 年以来,美国年轻人因合成阿片类药物过量死亡的人数增加了 300%以上,主要原因是海洛因和其他毒品被非法制造的芬太尼污染。快速检测条可用于检测药物样本(使用前)或尿液(使用后)中是否存在芬太尼,这可能有助于人们了解自己的暴露风险。本研究旨在确定使用毒品的年轻人是否愿意将快速检测条用作减少伤害的干预措施来预防过量用药。我们假设曾有过用药过量的人会更愿意使用检测条。

方法

我们于 2017 年 5 月至 9 月在罗德岛招募了使用毒品的便利样本的年轻人。合格的参与者(年龄在 18 至 35 岁之间,过去 30 天内有过药物使用)完成了访谈者管理的调查。该调查评估了参与者的社会人口学和行为特征、过量用药风险以及疑似芬太尼暴露情况,以及是否愿意使用带至家中的快速检测条来检测药物或尿液中的芬太尼污染。然后,参与者接受了检测条的使用培训,并获得了 10 条带回家。

结果

在 93 名符合条件的参与者中,平均年龄为 27 岁(标准差=4.8),56%(n=52)的参与者为男性,56%(n=52)为白人。超过三分之一(n=34,37%)有过用药过量史。绝大多数(n=86,92%)的参与者希望在使用药物之前知道药物中是否含有芬太尼。65 名(70%)参与者报告担心他们的药物被芬太尼污染。经过简短的培训,近所有参与者(n=88,95%)表示计划使用检测条。

结论

超过 90%的参与者表示愿意使用快速检测条,无论是否有过用药过量史,这表明快速芬太尼检测在罗德岛使用毒品的年轻人中是一种可接受的减少伤害的干预措施。研究正在进行后续随访,以确定参与者在何种情况下、如何以及是否使用了快速检测条,以及阳性结果是否导致了用药过量风险行为的改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b76e/5806485/d2d0cf0092e3/12954_2018_213_Fig1_HTML.jpg

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