Liu Tiffany Sara, Meskin Seth
Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, CT, USA.
Middle East Afr J Ophthalmol. 2017 Oct-Dec;24(4):216-218. doi: 10.4103/meajo.MEAJO_304_16.
The purpose of the study was to report a case of focal trichiasis causing full-thickness corneal edema, scarring, and endothelial cell loss requiring penetrating keratoplasty (PK). A 66-year-old male was referred for trichiasis of the right upper eyelid corresponding to an area of full-thickness corneal edema. No keratic precipitates or guttata was noted. Specular microscopy showed diffuse endothelial cell loss. He was treated with topical steroids and acyclovir with epilation of lashes. Anterior chamber paracentesis was negative for varicella-zoster virus, cytomegalovirus, and herpes simplex virus. The patient developed diffuse stromal scarring with a decrease in vision and ultimately underwent PK with preceding eyelid repair. To the best of our knowledge, we present the first reported case of chronic trichiasis causing full-thickness corneal edema, scarring, and endothelial cell loss requiring PK.
本研究的目的是报告一例因局限性倒睫导致角膜全层水肿、瘢痕形成及内皮细胞丢失而需行穿透性角膜移植术（PK）的病例。一名66岁男性因右上睑倒睫伴相应区域角膜全层水肿前来就诊。未发现角膜后沉着物或角膜小滴。镜面显微镜检查显示内皮细胞弥漫性丢失。给予局部类固醇和阿昔洛韦治疗，并拔除睫毛。前房穿刺检查水痘-带状疱疹病毒、巨细胞病毒和单纯疱疹病毒均为阴性。患者出现弥漫性基质瘢痕形成，视力下降，最终先行眼睑修复，然后接受了穿透性角膜移植术。据我们所知，我们报告了首例因慢性倒睫导致角膜全层水肿、瘢痕形成及内皮细胞丢失而需行穿透性角膜移植术的病例。
