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活体肝移植中供者手术切口的现状——日本全国性调查。

Current Status of Surgical Incisions Used in Donors During Living Related Liver Transplantation-A Nationwide Survey in Japan.

机构信息

Department of Hepatobiliary and Pancreatic Surgery, Gunma University, Maebashi, Japan.

Department of Surgery and Science, Kyushu University, Fukuoka, Japan.

出版信息

Transplantation. 2018 Aug;102(8):1293-1299. doi: 10.1097/TP.0000000000002126.

Abstract

BACKGROUND

Smaller surgical incisions have recently been introduced in living donor liver procurement. This study used national data from Japan to clarify the present status of surgical incisions in living donor liver procurement.

METHODS

A nationwide, questionnaire-based survey related to 3121 donors and recipients was used. Donors were divided into 2 groups: left lateral segment graft (LLSG) procurement (n = 690) and other types (n = 2431). Incisions were classified into 6 types: type I, upper midline and bilateral subcostal; type II, upper midline and right subcostal; type III, upper midline and right subcostal to the right lateral margin of the abdominal rectus muscle; type IV, upper midline without laparoscopy; type V, upper midline with laparoscopy; and type VI, lower abdominal using the full laparoscopic technique. Types I, II, and III were regarded as standard, and types IV, V, and VI as small incisions.

RESULTS

In LLSGs, blood transfusion and postoperative complication rates were significantly less frequent in the small incision group than in the standard group. In other graft types, there were no significant differences in blood transfusion, postoperative complication, and recipients' graft loss rates. The rates of wound extension during surgery were 2.8% and 2.1% in the small incision group in LLSGs and in other graft types, respectively. A small incision was adapted more frequently and postoperative complications were less common in high-volume centers.

CONCLUSIONS

Various incisions have been adopted in living donor liver procurement. Donor safety and graft integrity appear to have been retained for donors receiving small incisions.

摘要

背景

活体肝移植供肝切取术式已由大切口向小切口转变。本研究旨在利用日本全国性数据阐明活体肝移植供肝切取术式的现状。

方法

本研究采用基于问卷调查的全国性研究,共纳入 3121 例供体和受体。供体分为左外叶组(n=690)和其他类型组(n=2431)。切口分为 6 种类型:Ⅰ型,上正中切口联合双侧肋缘下切口;Ⅱ型,上正中切口联合右肋缘下切口;Ⅲ型,上正中切口联合右肋缘下至腹直肌外侧缘切口;Ⅳ型,无腹腔镜的上正中切口;Ⅴ型,联合腹腔镜的上正中切口;Ⅵ型,完全腹腔镜下腹膜外切口。Ⅰ、Ⅱ和Ⅲ型为标准切口,Ⅳ、Ⅴ和Ⅵ型为小切口。

结果

在左外叶组中,小切口组的输血率和术后并发症发生率明显低于标准组。在其他类型供肝中,小切口组和标准组在输血、术后并发症和受体移植物丢失率方面均无显著差异。小切口组术中切口延长率在左外叶组和其他类型供肝中分别为 2.8%和 2.1%。在大手术量中心,小切口的应用更为频繁,术后并发症发生率更低。

结论

活体肝移植供肝切取术式多样,小切口对供体安全和移植物完整性无影响。

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